#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4380745	Binding	Protac activity at VHL/EGFR exon 19 deletion mutant in human HCC827 cells assessed as reduction in EGFR autophosphorylation up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	2	ALA4376874	cell-based format	Scientific Literature
2.	ALA4380746	Binding	Protac activity at VHL/EGFR L858R mutant in human H3255 cells assessed as reduction in EGFR autophosphorylation up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	2	ALA4376874	cell-based format	Scientific Literature
3.	ALA4380747	Binding	Protac activity at VHL/EGFR exon 19 deletion mutant in human HCC827 cells assessed as reduction in AKT phosphorylation up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	2	ALA4376874	cell-based format	Scientific Literature
4.	ALA4380748	Binding	Protac activity at VHL/EGFR L858R mutant in human H3255 cells assessed as reduction in AKT phosphorylation up to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	2	ALA4376874	cell-based format	Scientific Literature
5.	ALA4380755	Binding	Protac activity at VHL/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation up to 500 nM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4376874	cell-based format	Scientific Literature
6.	ALA4380756	Binding	Protac activity at VHL/EGFR L858R mutant in human H3255 cells assessed as induction of EGFR degradation up to 500 nM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4376874	cell-based format	Scientific Literature
7.	ALA4380757	Binding	Protac activity at VHL/EGFR exon 19 deletion mutant in human HCC827 cells assessed as induction of EGFR degradation at 1 to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4376874	cell-based format	Scientific Literature
8.	ALA4380758	Binding	Protac activity at VHL/EGFR L858R mutant in human H3255 cells assessed as induction of EGFR degradation at 1 to 10 uM treated 8 hrs post serum starvation measured after 16 hrs by Western blot analysis	Homo sapiens	1	ALA4376874	cell-based format	Scientific Literature
9.	ALA4380798	Functional	Antiproliferative activity against human H3255 cells measured after 3 days by CCK8 assay	Homo sapiens	6	ALA4376874	cell-based format	Scientific Literature
10.	ALA4710101	Binding	Protac activity at VHL/EGFR del19 mutant in human HCC827 cells assessed as induction of EGFR degradation measured after 24 hrs by Western blot analysis	Homo sapiens	1	ALA4706553	cell-based format	Scientific Literature
11.	ALA5105246	Physicochemical	Thermodynamic solubility of the compound in phosphate buffer at pH 7 incubated for 1 hr by shake flask based HPLC-UV analysis		28	ALA5104112	small-molecule physicochemical format	Scientific Literature
12.	ALA5136273	Binding	PROTAC activity at VHL/wild type EGFR in human OVCAR-8 cells assessed as EGFR degradation measured after 24 hrs by Immunoblotting analysis	Homo sapiens	2	ALA5131542	cell-based format	Scientific Literature
13.	ALA5136274	Binding	PROTAC activity at VHL/EGFR Del19 mutant in human HCC827 cells assessed as EGFR degradation measured after 24 hrs by Immunoblotting analysis	Homo sapiens	1	ALA5131542	cell-based format	Scientific Literature
14.	ALA5137694	Binding	Protac activity against VHL/EGFR deletion 19 mutant in human HCC827 cells	Homo sapiens	1	ALA5136974	cell-based format	Scientific Literature
15.	ALA5137695	Binding	Protac activity against VHL/EGFR deletion 19 mutant in human HCC827 cells relative to control	Homo sapiens	1	ALA5136974	cell-based format	Scientific Literature
16.	ALA5137696	Binding	Protac activity against VHL/EGFR L858R mutant in human HCC827 cells	Homo sapiens	1	ALA5136974	cell-based format	Scientific Literature
17.	ALA5137697	Binding	Protac activity against VHL/EGFR L858R mutant in human HCC827 cells relative to control	Homo sapiens	1	ALA5136974	cell-based format	Scientific Literature
18.	ALA5160878	Binding	Protac activity at VHL/EGFR deletion19 mutant in human HCC827 cells assessed as induction of EGFR degradation	Homo sapiens	3	ALA5154782	cell-based format	Scientific Literature