# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4417106 | B | Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged GGPPS expressed in Escherichia coli BL21 (DE3) using FPP and [14C] IPP as substrate preincubated for 15 mins with FPP followed by [14C] IPP addition and further incubated for 20 mins by scintillation counting method | Homo sapiens | 57 | assay format | Scientific Literature | ||
2. | ALA4417107 | B | Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substrate preincubated for 30 mins followed by substrate addition by continuous spectrophotometric assay | Homo sapiens | 58 | assay format | Scientific Literature | ||
3. | ALA4417110 | B | Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) assessed as using GPP and IPP as substrate preincubated for 30 mins followed by substrate addition in presence of 0.01 % Triton X-100 by continuous spectrophotometric assay | Homo sapiens | 14 | assay format | Scientific Literature | ||
4. | ALA4417111 | B | Inhibition of human N-terminal TEV protease cleavage site-fused-His6-tagged FPPS expressed in Escherichia coli BL21 (DE3) using GPP and IPP as substrate preincubated for 30 mins followed by substrate addition in absence of 0.01 % Triton X-100 by continuous spectrophotometric assay | Homo sapiens | 14 | assay format | Scientific Literature | ||
5. | ALA4417124 | F | Cytotoxicity against human PANC1 cells assessed as decrease in cell growth measured after 72 hrs by MTT assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
6. | ALA4417125 | F | Cytotoxicity against human MIAPaCa2 cells assessed as decrease in cell growth measured after 72 hrs by MTT assay | Homo sapiens | 32 | cell-based format | Scientific Literature |