| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4340214 | B | Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | Mus musculus | 25 | ALA4339228 | cell-based format | Scientific Literature | |
| 2. | ALA4340215 | B | Inhibition of pH 5.5-stimulated mouse ASIC2a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | Mus musculus | 25 | ALA4339228 | cell-based format | Scientific Literature | |
| 3. | ALA4340216 | B | Inhibition of pH 6.25-stimulated mouse ASIC1a/2a heterodimer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay | Mus musculus | 25 | ALA4339228 | cell-based format | Scientific Literature | |
| 4. | ALA4340217 | P | Kinetic solubility of the compound at pH 7.4 | 3 | ALA4339228 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA4340218 | A | Binding affinity to human serum albumin by NMR-based analysis | Homo sapiens | 3 | ALA4339228 | single protein format | Scientific Literature | |
| 6. | ALA4340219 | B | Inhibition of human ERG incubated for 4 hrs by fluorescence polarization assay | Homo sapiens | 3 | ALA4339228 | single protein format | Scientific Literature | |
| 7. | ALA4340220 | A | Inhibition of CYP1A2 (unknown origin) using pro-luciferin substrates in presence of NADPH by firefly luciferase reporter gene based P450-Glo assay | Homo sapiens | 3 | ALA4339228 | single protein format | Scientific Literature | |
| 8. | ALA4340221 | A | Inhibition of CYP2D6 (unknown origin) using pro-luciferin substrates in presence of NADPH by firefly luciferase reporter gene based P450-Glo assay | Homo sapiens | 1 | ALA4339228 | single protein format | Scientific Literature | |
| 9. | ALA4340222 | A | Clearance in NMRI mouse at 1 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 3 | ALA4339228 | organism-based format | Scientific Literature | |
| 10. | ALA4340223 | A | Volume of distribution in NMRI mouse at 1 mg/kg, iv by LC-MS/MS analysis | Mus musculus | 3 | ALA4339228 | organism-based format | Scientific Literature | |
| 11. | ALA4340224 | A | Cmax in NMRI mouse at 3 mg/kg, po by LC-MS/MS analysis | Mus musculus | 3 | ALA4339228 | organism-based format | Scientific Literature | |
| 12. | ALA4340225 | A | Oral bioavailability in NMRI mouse at 3 mg/kg by LC-MS/MS analysis | Mus musculus | 3 | ALA4339228 | organism-based format | Scientific Literature | |
| 13. | ALA4340226 | A | Ratio of drug level in brain to plasma of NMRI mouse at 1 mg/kg, iv measured after 2 to 8 hrs post dose | Mus musculus | 3 | ALA4339228 | organism-based format | Scientific Literature |
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