| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4344938 | B | Activation of ATF6 in NRVM isolated from Sprague-Dawley rat assessed as increase in catalase expression at 10 uM using compound pre-activated with hydrogen peroxide for 8 hrs prior to NRVM treatment and measured after 16 hrs by SYBR green dye-based qRT-PCR analysis | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
| 2. | ALA4344944 | A | Prodrug conversion in HBS buffer assessed as peroxide-mediated formation of N-(2-hydroxy-5-methylphenyl)-3-phenylpropanamide at pH 7.4 and 37 degree C incubated for 24 hrs in presence of 20 molar equivalent peroxide by LC-MS analysis analysis | 1 | assay format | Scientific Literature | |||
| 3. | ALA4344945 | A | Prodrug conversion in HBS buffer assessed as peroxide-mediated formation of N-[2-[2-(4-hydroxyphenyl)ethoxy]-5-methylphenyl]-3-phenylpropanamide at pH 7.4 and 37 degree C incubated for 24 hrs in presence of 20 molar equivalent peroxide by LC-MS analysis analysis | 1 | assay format | Scientific Literature | |||
| 4. | ALA4344949 | B | Activation of ATF6 in NRVM isolated from Sprague-Dawley rat assessed as increase in GRP78 expression at 10 uM using compound pre-activated with hydrogen peroxide for 8 hrs prior to NRVM treatment and measured after 16 hrs by SYBR green dye-based qRT-PCR analysis | Rattus norvegicus | 2 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!