#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4324918	Functional	Agonist activity at mouse mu opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP formation incubated for 8 min followed by forskolin stimulation by ELISA	Mus musculus	4	ALA4321862	cell-based format	Scientific Literature
2.	ALA4324921	Binding	Displacement of [3H]-Naloxone from mouse mu opioid receptor expressed in CHO cells incubated for 1.5 hrs by competitive radioligand binding assay	Mus musculus	25	ALA4321862	cell-based format	Scientific Literature
3.	ALA4324922	ADME	Displacement of [3H]-Naltrindole from mouse kappa opioid receptor expressed in CHO cells incubated for 1.5 hrs by competitive radioligand binding assay	Mus musculus	24	ALA4321862	cell-based format	Scientific Literature
4.	ALA4324923	ADME	Displacement of [3H]-norBNI from human delta opioid receptor expressed in CHO cells incubated for 1.5 hrs by competitive radioligand binding assay	Homo sapiens	24	ALA4321862	cell-based format	Scientific Literature
5.	ALA4324924	Unassigned	Selectivity index, ratio of Ki for mouse kappa opioid receptor expressed in CHO cells to Ki for mouse mu opioid receptor expressed in CHO cells	Mus musculus	25	ALA4321862	cell-based format	Scientific Literature
6.	ALA4324925	Unassigned	Selectivity index, ratio of Ki for human delta opioid receptor expressed in CHO cells to Ki for mouse mu opioid receptor expressed in CHO cells	Mus musculus	24	ALA4321862	cell-based format	Scientific Literature
7.	ALA4324926	Functional	Agonist activity at recombinant mouse mu opioid receptor expressed in CHO cell membrane assessed as [35]-GTPgammaS binding incubated for 1.5 hrs by scintillation counting method	Mus musculus	25	ALA4321862	cell-based format	Scientific Literature
8.	ALA4324927	Functional	Agonist activity at recombinant mouse mu opioid receptor expressed in CHO cell membrane assessed as [35]-GTPgammaS binding incubated for 1.5 hrs by scintillation counting method relative to DAMGO	Mus musculus	25	ALA4321862	cell-based format	Scientific Literature
9.	ALA4324930	Functional	Inhibition of morphine-induced antinociceptive activity in Swiss Webster mouse assessed as decrease in latency to tail withdrawal at 10 mg/kg, sc administered 5 mins before morphine stimulation observed for 20 mins by warm water tail withdrawal assay	Mus musculus	7	ALA4321862	organism-based format	Scientific Literature
10.	ALA4324931	Functional	Inhibition of morphine-induced antinociceptive activity in subcutaneously dosed Swiss Webster mouse assessed as decrease in latency to tail withdrawal administered 5 mins before morphine stimulation observed for 20 mins by warm water tail withdrawal assay	Mus musculus	8	ALA4321862	organism-based format	Scientific Literature
11.	ALA4324932	Functional	Agonist activity at mouse mu opioid receptor expressed in CHO cells cotransfected with Galphaqi5 assessed as intracellular calcium level preincubated for 60 mins in Fluo4AM solution followed by compound addition by Fluo4AM dye based assay	Mus musculus	3	ALA4321862	cell-based format	Scientific Literature
12.	ALA4324933	Functional	Antagonist activity at mouse mu opioid receptor expressed in CHO cells cotransfected with Galphaqi5 assessed as inhibition of DAMGO-induced increase in intracellular calcium concentration preincubated for 60 mins in Fluo4AM solution followed by compound addition and further incubated for 15 mins followed by DAMGO stimulation by Fluo4AM dye based assay	Mus musculus	4	ALA4321862	cell-based format	Scientific Literature
13.	ALA4324934	Functional	Agonist activity at mouse mu opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP formation incubated for 8 min followed by forskolin stimulation by ELISA (Rvb = 0 %)	Mus musculus	4	ALA4321862	cell-based format	Scientific Literature
14.	ALA4324935	Toxicity	Toxicity in placebo-pelleted Swiss Webster mouse assessed as wet dog shakes at 20 mg/kg, sc observed after 20 mins	Mus musculus	1	ALA4321862	organism-based format	Scientific Literature
15.	ALA4324936	Toxicity	Toxicity in placebo-pelleted Swiss Webster mouse assessed as escape jumps at 20 mg/kg, sc observed after 20 mins	Mus musculus	1	ALA4321862	organism-based format	Scientific Literature
16.	ALA4324937	Toxicity	Toxicity in placebo-pelleted Swiss Webster mouse assessed as paw tremors at 20 mg/kg, sc observed after 20 mins	Mus musculus	1	ALA4321862	organism-based format	Scientific Literature
17.	ALA4324938	Functional	Inhibition of opioid-withdrawal symptom in morphine-pelleted Swiss Webster mouse assessed as reduction in wet dog shakes at 1 mg/kg, sc observed after 20 mins	Mus musculus	4	ALA4321862	organism-based format	Scientific Literature
18.	ALA4324939	Functional	Inhibition of opioid-withdrawal symptom in morphine-pelleted Swiss Webster mouse assessed as reduction in escape jumps at 1 mg/kg, sc observed after 20 mins	Mus musculus	4	ALA4321862	organism-based format	Scientific Literature
19.	ALA4324940	Functional	Inhibition of opioid-withdrawal symptom in morphine-pelleted Swiss Webster mouse assessed as reduction in paw tremors at 1 mg/kg, sc observed after 20 mins	Mus musculus	4	ALA4321862	organism-based format	Scientific Literature
20.	ALA4324944	Functional	Inhibition of opioid-withdrawal symptom in morphine-pelleted Swiss Webster mouse assessed as reduction in wet dog shakes at 50 mg/kg, sc observed after 20 mins	Mus musculus	1	ALA4321862	organism-based format	Scientific Literature