# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4391118 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 16 | ALA4390650 | cell-based format | Scientific Literature | |
2. | ALA4391119 | F | Cytotoxicity against human MDA-MB-453 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 16 | ALA4390650 | cell-based format | Scientific Literature | |
3. | ALA4391120 | A | Cytotoxicity against human MCF10A cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 16 | ALA4390650 | cell-based format | Scientific Literature | |
4. | ALA4391121 | F | Induction of apoptosis in human MDA-MB-453 cells at 10 uM incubated for 48 hrs by acridine orange and ethidium bromide staining based inverted fluorescent microscopy | Homo sapiens | 1 | ALA4390650 | cell-based format | Scientific Literature | |
5. | ALA4391122 | F | Induction of necrosis in human MDA-MB-453 cells at 10 uM incubated for 48 hrs by acridine orange and ethidium bromide staining based inverted fluorescent microscopy | Homo sapiens | 1 | ALA4390650 | cell-based format | Scientific Literature | |
6. | ALA4391123 | F | Induction of morphological changes in human MDA-MB-453 cell assessed as induction of cell membrane blebbing at 10 uM incubated for 48 hrs by acridine orange and ethidium bromide staining based inverted fluorescent microscopy | Homo sapiens | 1 | ALA4390650 | cell-based format | Scientific Literature | |
7. | ALA4391124 | F | Induction of morphological changes in human MDA-MB-453 cell assessed as induction of protrusion elongation at 10 uM incubated for 48 hrs by acridine orange and ethidium bromide staining based inverted fluorescent microscopy | Homo sapiens | 1 | ALA4390650 | cell-based format | Scientific Literature | |
8. | ALA4391125 | F | Induction of morphological changes in human MDA-MB-453 cell assessed as induction of chromatin condensation at 10 uM incubated for 48 hrs by acridine orange and ethidium bromide staining based inverted fluorescent microscopy | Homo sapiens | 1 | ALA4390650 | cell-based format | Scientific Literature | |
9. | ALA4391126 | F | Induction of apoptosis in human MDA-MB-453 cells assessed as increase in SMAD7 protein expression at 10 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4390650 | cell-based format | Scientific Literature | |
10. | ALA4391127 | F | Induction of apoptosis in human MDA-MB-453 cells assessed as increase in p53 protein expression incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4390650 | cell-based format | Scientific Literature | |
11. | ALA4391128 | B | Inhibition of DNMT1 (unknown origin) at 100 uM using cytosine-rich DNA substrate by ELISA relative to untreated control | Homo sapiens | 1 | ALA4390650 | single protein format | Scientific Literature | |
12. | ALA4391129 | B | Inhibition of DNMT3B (unknown origin) at 100 uM using cytosine-rich DNA substrate by ELISA relative to untreated control | Homo sapiens | 1 | ALA4390650 | single protein format | Scientific Literature |