Assay

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Assay

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	#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
	1.	ALA4422592	B	Inhibition of StrepTag-tagged human SARM1 TIR (561 to 724 residues) expressed in NRK1-HEK293T cells assessed as reduction in NADase activity by measuring NAD consumption at 150 uM pre-incubated up to 120 mins before NAD+ addition and further incubated for 60 mins by HPLC analysis relative to control	Homo sapiens	6	ALA4421736	cell-based format	Patent Bioactivity Data
	2.	ALA4422593	B	Inhibition of StrepTag-tagged human SARM1 TIR (561 to 724 residues) expressed in NRK1-HEK293T cells assessed as reduction in NADase activity by measuring ADPR production at 150 uM pre-incubated up to 120 mins before NAD+ addition and further incubated for 60 mins by HPLC analysis	Homo sapiens	6	ALA4421736	cell-based format	Patent Bioactivity Data