| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4426525 | Binding | Inhibition of MDR1 (unknown origin) expressed in MDCK cells assessed as decrease in calcein-AM transport after 30 mins by fluorescence assay | Homo sapiens | 14 | ALA4425124 | cell-based format | Scientific Literature | |
| 2. | ALA4426526 | Binding | Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as decrease in calcein-AM transport at 10'-4 M after 30 mins by fluorescence assay | Homo sapiens | 14 | ALA4425124 | cell-based format | Scientific Literature | |
| 3. | ALA4426527 | ADME | Substrate activity at p-gp in human Caco2 cells assessed as ratio of apparent permeability across basolateral to apical over apical to basolateral side at 100 uM after 120 mins by UV-Vis spectroscopy | Homo sapiens | 14 | ALA4425124 | cell-based format | Scientific Literature | |
| 4. | ALA4426528 | Binding | Activation of MDR1 (unknown origin) ATPase activity expressed in MDCK cells assessed as decrease in ATP level after 2 hrs by ATPlite assay | Homo sapiens | 14 | ALA4425124 | cell-based format | Scientific Literature |
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