# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4401997 | B | Inhibition of rat neuronal NOS expressed in Escherichia coli using L-arginine as substrate in presence of human oxyhemoglobin after 6 mins by hemoglobin NO capture assay | Rattus norvegicus | 21 | assay format | Scientific Literature | ||
2. | ALA4401998 | B | Inhibition of human neuronal NOS expressed in Escherichia coli using L-arginine as substrate in presence of human oxyhemoglobin after 6 mins by hemoglobin NO capture assay | Homo sapiens | 21 | assay format | Scientific Literature | ||
3. | ALA4401999 | B | Selectivity ratio of Ki for human neuronal NOS to Ki for rat neuronal NOS | 21 | assay format | Scientific Literature | |||
4. | ALA4402000 | A | Effective permeability of the compound at 200 uM after 17 hrs by PAMPA-BBB assay | 21 | assay format | Scientific Literature | |||
5. | ALA4402001 | A | Apparent permeability from apical to basolateral side in human Caco2 cells at 5 uM after 90 mins | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
6. | ALA4402002 | A | Apparent permeability from basolateral to apical side in human Caco2 cells at 5 uM after 90 mins | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
7. | ALA4402003 | A | Efflux ratio of apparent permeability in human Caco2 cells at 5 uM after 90 mins | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
8. | ALA4402004 | A | Inhibition of human endothelial NOS expressed in Escherichia coli using L-arginine as substrate in presence of human oxyhemoglobin after 6 mins by hemoglobin NO capture assay | Homo sapiens | 7 | assay format | Scientific Literature | ||
9. | ALA4402005 | A | Inhibition of human iNOS expressed in Escherichia coli using L-arginine as substrate in presence of human oxyhemoglobin after 6 mins by hemoglobin NO capture assay | Homo sapiens | 7 | assay format | Scientific Literature | ||
10. | ALA4402006 | A | Inhibition of mouse iNOS expressed in Escherichia coli using L-arginine as substrate in presence of human oxyhemoglobin after 6 mins by hemoglobin NO capture assay | Mus musculus | 7 | assay format | Scientific Literature | ||
11. | ALA4402007 | B | Selectivity ratio of Ki for human endothelial NOS to Ki of human neuronal NOS | Homo sapiens | 7 | assay format | Scientific Literature | ||
12. | ALA4402008 | B | Selectivity ratio of Ki for human iNOS to Ki of human neuronal NOS | Homo sapiens | 7 | assay format | Scientific Literature | ||
13. | ALA4402009 | B | Selectivity ratio of Ki for rat endothelial NOS to Ki of mouse iNOS | Rattus norvegicus | 7 | assay format | Scientific Literature |