| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4406418 | B | Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 10 | ALA4402606 | cell-based format | Scientific Literature | |
| 2. | ALA4406419 | B | Inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incubated for 5 mins followed by NADPH addition and measured after 20 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 10 | ALA4402606 | cell-based format | Scientific Literature | |
| 3. | ALA4406420 | B | Ratio of IC50 for inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate incubated for 5 mins followed by NADPH addition and measured after 20 mins to IC50 for inhibition of CYP4Z1 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using luciferin-benzyl ether as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 10 | ALA4402606 | cell-based format | Scientific Literature | |
| 4. | ALA4406421 | A | Inhibition of recombinant human CYP4A11 expressed in baculovirus infected insect cells at 30 uM using Luc-4A as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 4 | ALA4402606 | cell-based format | Scientific Literature | |
| 5. | ALA4406425 | A | Inhibition of recombinant human CYP4F12 expressed in baculovirus infected insect cells at 30 uM using Luc-BE as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 8 | ALA4402606 | cell-based format | Scientific Literature | |
| 6. | ALA4406426 | A | Inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector at 30 uM using Luc-BE as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 4 | ALA4402606 | cell-based format | Scientific Literature |
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