# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4369494 | Functional | Antiviral activity against Vaccinia virus Copenhagen infected in African green monkey Vero cells assessed as inhibition of viral replication after 4 days by neural red dye-based spectrophotometric method | Vaccinia virus | 15 | ALA4368876 | organism-based format | Scientific Literature | |
2. | ALA4369495 | ADME | Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 4 days by neural red dye-based spectrophotometric method | Chlorocebus sabaeus | 15 | ALA4368876 | cell-based format | Scientific Literature | |
3. | ALA4369496 | Toxicity | Selectivity index, ratio of CC50 for African green monkey Vero cells to IC50 for Vaccinia virus Copenhagen infected in African green monkey Vero cells | 6 | ALA4368876 | assay format | Scientific Literature | ||
4. | ALA4369497 | ADME | Cytotoxicity against MDCK cells assessed as reduction in cell viability after 48 hrs by MTT assay | Canis lupus familiaris | 18 | ALA4368876 | cell-based format | Scientific Literature | |
5. | ALA4369498 | Functional | Antiviral activity against Influenza A virus (A/Puerto Rico/8/34(H1N1)) infected in MDCK cells assessed as reduction in virus titer pretreated with cells for 1 hr followed by viral infection for 1 hr and subsequent unbound virion washout measured after 24 to 48 hrs by hemagglutination test | Influenza A virus | 18 | ALA4368876 | organism-based format | Scientific Literature | |
6. | ALA4369499 | Toxicity | Selectivity index, ratio of CC50 for MDCK cells to IC50 for Influenza A virus (A/Puerto Rico/8/34(H1N1)) infected in MDCK cells | 12 | ALA4368876 | cell-based format | Scientific Literature | ||
7. | ALA4812011 | ADME | Cytotoxicity against MDCK cells by MTT assay | Canis lupus familiaris | 21 | ALA4811236 | cell-based format | Scientific Literature | |
8. | ALA4812012 | Functional | Antiviral activity against Hantaan 76-118 pseudovirus infected in MDCK cells assessed as reduction in virus replication incubated for 48 hrs by luminescence assay | Orthohantavirus hantanense | 21 | ALA4811236 | organism-based format | Scientific Literature | |
9. | ALA4812013 | Toxicity | Selective index, ratio of CC50 for MDCK cells to IC50 for Hantaan 76-118 | 13 | ALA4811236 | assay format | Scientific Literature | ||
10. | ALA4812014 | ADME | Cytotoxicity against human HEK293T cells measured after 72 hrs by MTT assay | Homo sapiens | 21 | ALA4811236 | cell-based format | Scientific Literature | |
11. | ALA4812015 | Functional | Antiviral activity against pseudotyped recombinant vesicular stomatitis virus delta G Gn-Gc infected HEK293T cells assessed as reduction in virus replication incubated for 48 hrs by luminescence assay | Vesicular stomatitis virus | 21 | ALA4811236 | organism-based format | Scientific Literature | |
12. | ALA4812016 | Toxicity | Selective index, ratio of CC50 for HEK293T cells to IC50 for antiviral activity against pseudotyped recombinant vesicular stomatitis virus delta G Gn-Gc infected HEK293T cells | 9 | ALA4811236 | assay format | Scientific Literature |