# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4406121 | Functional | Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 40 | ALA4402600 | cell-based format | Scientific Literature | |
2. | ALA4406122 | Functional | Cytotoxicity in human A375 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 40 | ALA4402600 | cell-based format | Scientific Literature | |
3. | ALA4406123 | Functional | Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 40 | ALA4402600 | cell-based format | Scientific Literature | |
4. | ALA4406124 | Functional | Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 40 | ALA4402600 | cell-based format | Scientific Literature | |
5. | ALA4406125 | Functional | Cytotoxicity in human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 40 | ALA4402600 | cell-based format | Scientific Literature | |
6. | ALA4406126 | Functional | Cytotoxicity in human OVCAR3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 39 | ALA4402600 | cell-based format | Scientific Literature | |
7. | ALA4406127 | Functional | Cytotoxicity in human Caov3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 40 | ALA4402600 | cell-based format | Scientific Literature | |
8. | ALA4406128 | Binding | Binding affinity to CDC20 (unknown origin) by SPR analysis | Homo sapiens | 4 | ALA4402600 | single protein format | Scientific Literature | |
9. | ALA4406138 | Functional | Inhibition of mitotic exit in human HepG2 cells assessed as increase in nuclear phosphohistone H3 levels incubated for 48 hrs by immunofluorescence assay | Homo sapiens | 3 | ALA4402600 | cell-based format | Scientific Literature | |
10. | ALA4406140 | Functional | Inhibition of mitotic exit in human HepG2 cells assessed as increase in nuclear phosphohistone H3 levels at 100 uM incubated for 48 hrs by immunofluorescence assay relative to control | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
11. | ALA4406143 | Functional | Inhibition of mitotic exit in human HepG2 cells assessed as increase in nuclear phosphohistone H3 levels at 0.03 to 0.3 uM incubated for 48 hrs by by Western blot analysis relative to control | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
12. | ALA4406144 | Binding | Inhibition of tubulin polymerization in human HepG2 cells assessed as disruption of microtubule organization in cytosol at 0.3 uM incubated for 48 hrs by immunofluorescent staining | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
13. | ALA4406145 | Binding | Inhibition of tubulin polymerization in human HepG2 cells assessed as condensed chromosome formation at 0.3 uM incubated for 48 hrs by immunofluorescent staining | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
14. | ALA4406146 | Binding | Inhibition of porcine brain tubulin polymerization assessed as reduction in rate and extent of tubulin assembly measured at 37 degC every 30 secs for 60 mins by fluorescence based assay | Sus scrofa | 1 | ALA4402600 | assay format | Scientific Literature | |
15. | ALA4406152 | Functional | Induction of apoptosis in human HepG2 cells assessed as increase in cleaved PARP level at 0.03 to 0.3 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
16. | ALA4406153 | Functional | Induction of apoptosis in human HepG2 cells assessed as increase in cleaved caspase-3 level at 0.03 to 0.3 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
17. | ALA4406154 | Functional | Inhibition of cell migration in human HepG2 cells incubated for 48 hrs by wound healing assay | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
18. | ALA4406155 | Functional | Inhibition of cell invasion in human HepG2 cells assessed as retardation of cell penetration through matrigel-coated membranes at 0.3 uM incubated for 48 hrs | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
19. | ALA4406164 | Functional | Induction of apoptosis in human HepG2 cells assessed as viable cells level at 0.3 uM incubated for 24 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 89.38%) | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature | |
20. | ALA4406165 | Functional | Induction of apoptosis in human HepG2 cells assessed as early apoptotic cells level at 0.3 uM incubated for 24 hrs by Annexin V-FITC/PI staining based flow cytometry (Rvb = 4.02%) | Homo sapiens | 1 | ALA4402600 | cell-based format | Scientific Literature |