# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5256107 | F | Antitumor activity against human WM164 cells assessed as reduction in metastasis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA5256108 | F | Antitumor activity against human A-375 cells assessed as reduction in metastasis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA5256109 | F | Antitumor activity against human M14 cells assessed as reduction in metastasis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4366984 | F | Antiproliferative activity against human A375 cells after 72 hrs by MTT assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
5. | ALA4366985 | F | Antiproliferative activity against human M14 cells after 72 hrs by MTT assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
6. | ALA4366986 | F | Antiproliferative activity against human WM164 cells after 72 hrs by MTT assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
7. | ALA4366987 | B | Inhibition of bovine brain tubulin polymerization at 10 uM measured at time interval of 1 mins for 20 mins by spectrophotometric analysis | Bos taurus | 2 | assay format | Scientific Literature | ||
8. | ALA4366988 | B | Disruption of microtubule network in human WM164 cells assessed as microtubule fragmentation at 100 nM after 18 hrs by DAPI staining based fluorescence confocal microscopic method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA4366989 | B | Disruption of microtubule network in human WM164 cells assessed as microtubule disassembly at 100 nM after 18 hrs by DAPI staining based fluorescence confocal microscopic method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA4366990 | F | Inhibition of anchorage-dependent colony formation in human A375 cells assessed as decrease in colony number at 5 nM after 12 days by crystal violet-staining based assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
11. | ALA4366991 | F | Antimigratory activity in human A375 cells assessed as wound closure at 5 nM after 22 hrs by scratch migration assay (Rvb = 60.7 +/- 3.5%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
12. | ALA4366992 | F | Antimigratory activity in human A375 cells assessed as wound closure at 25 nM after 22 hrs by scratch migration assay (Rvb = 60.7 +/- 3.5%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
13. | ALA4366993 | F | Antimigratory activity in human RPMI7951 cells assessed as wound closure at 25 nM after 18 hrs by scratch migration assay (Rvb = 71.8 +/- 1.8%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
14. | ALA4366994 | A | Half-life in CD-1 mouse liver microsomes in presence of NADPH regenerating system measured up to 4 hrs by UPLC-MS analysis | Mus musculus | 5 | microsome format | Scientific Literature | ||
15. | ALA4366995 | A | Intrinsic clearance in CD-1 mouse liver microsomes in presence of NADPH regenerating system measured up to 4 hrs by UPLC-MS analysis | Mus musculus | 5 | microsome format | Scientific Literature | ||
16. | ALA4366996 | A | Half-life in rat liver microsomes pre-incubated for 15 mins followed by addition of NADPH regenerating system by LC-MS analysis | Rattus norvegicus | 5 | microsome format | Scientific Literature | ||
17. | ALA4366997 | A | Intrinsic clearance in rat liver microsomes pre-incubated for 15 mins followed by addition of NADPH regenerating system by LC-MS analysis | Rattus norvegicus | 5 | microsome format | Scientific Literature | ||
18. | ALA4366998 | A | Half-life in human liver microsomes in presence of NADPH regenerating system | Homo sapiens | 5 | microsome format | Scientific Literature | ||
19. | ALA4366999 | A | Intrinsic clearance in human liver microsomes in presence of NADPH regenerating system | Homo sapiens | 5 | microsome format | Scientific Literature | ||
20. | ALA4367000 | T | Toxicity in ip dosed ICR mouse assessed as maximum tolerated dose | Mus musculus | 1 | organism-based format | Scientific Literature |