# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4373362 | B | Agonist activity at full length human LXRalpha expressed in HEK293 cells harboring LXRE-Luc promoter by luciferase reporter gene assay | Homo sapiens | 24 | ALA4371087 | cell-based format | Scientific Literature | |
2. | ALA4373363 | B | Agonist activity at full length human LXRalpha expressed in HEK293 cells harboring LXRE-Luc promoter at 10 uM by luciferase reporter gene assay relative to T0901317 | Homo sapiens | 30 | ALA4371087 | cell-based format | Scientific Literature | |
3. | ALA4373364 | B | Agonist activity at full length human LXRbeta expressed in HEK293 cells harboring LXRE-Luc promoter by luciferase reporter gene assay | Homo sapiens | 22 | ALA4371087 | cell-based format | Scientific Literature | |
4. | ALA4373365 | B | Agonist activity at full length human LXRbeta expressed in HEK293 cells harboring LXRE-Luc promoter at 10 uM by luciferase reporter gene assay relative to T0901317 | Homo sapiens | 30 | ALA4371087 | cell-based format | Scientific Literature | |
5. | ALA4373366 | B | Selectivity ratio of EC50 for full length human LXRalpha expressed in HEK293 cells to EC50 for full length human LXRbeta expressed in HEK293 cells | Homo sapiens | 21 | ALA4371087 | cell-based format | Scientific Literature | |
6. | ALA4373367 | A | Full agonist activity at LXR in human HepG2 cells assessed as increase in FASN mRNA level at 10 uM after 24 hrs by qPCR analysis relative to control | Homo sapiens | 5 | ALA4371087 | cell-based format | Scientific Literature | |
7. | ALA4373368 | A | Full agonist activity at LXR in human HepG2 cells assessed as increase in SREBP-1c mRNA level at 10 uM after 24 hrs by qPCR analysis relative to control | Homo sapiens | 5 | ALA4371087 | cell-based format | Scientific Literature |