| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4406714 | B | Inhibition of HIV-1 protease | Human immunodeficiency virus 1 | 13 | single protein format | Scientific Literature | ||
| 2. | ALA4406715 | F | Antiviral activity against HIV1 LAI infected in human MT2 cells | Human immunodeficiency virus 1 | 14 | organism-based format | Scientific Literature | ||
| 3. | ALA4406716 | F | Antiviral activity against HIV1 NL4-3 infected in human MT4 cells assessed as reduction in p24 Gag protein production | Human immunodeficiency virus 1 | 4 | organism-based format | Scientific Literature | ||
| 4. | ALA4406717 | F | Antiviral activity against atazanavir resistant HIV1 harboring protease L23I/E34Q/K43I/M46I/I50L/G51A/L63P/A71V/V82A/T91A mutant infected in human MT4 cells assessed as reduction in p24 Gag production | Human immunodeficiency virus 1 | 4 | organism-based format | Scientific Literature | ||
| 5. | ALA4406718 | F | Antiviral activity against lopinavir resistant HIV1 harboring protease L10F/V32I/M46I/I47A/A71V/I84V mutant infected in human MT4 cells assessed as inhibition of p24 Gag production | Human immunodeficiency virus 1 | 4 | organism-based format | Scientific Literature | ||
| 6. | ALA4406719 | F | Antiviral activity against darunavir resistant HIV1 harboring protease P30 L10I/I15V/K20R/L24I/V32I/M36I/ M46L/L63P/K70Q/V82A/I84V/L89M mutant infected in human MT4 cells assessed as reduction in p24 Gag production | Human immunodeficiency virus 1 | 4 | organism-based format | Scientific Literature | ||
| 7. | ALA4406720 | F | Selectivity ratio of IC50 for antiviral activity against atazanavir resitant HIV1 harboring protease L23I/E34Q/K43I/M46I/I50L/G51A/L63P/A71V/V82A/T91A mutant infected in human MT4 cells to IC50 for antiviral activity against wild-type HIV1 NL4-3 | 4 | cell-based format | Scientific Literature | |||
| 8. | ALA4406721 | F | Selectivity ratio of IC50 for antiviral activity against lopinavir resistant HIV1 harboring protease L10F/V32I/M46I/I47A/A71V/I84V mutant infected in human MT4 cells to IC50 for antiviral activity against wild-type HIV1 NL4-3 | 4 | cell-based format | Scientific Literature | |||
| 9. | ALA4406722 | F | Selectivity ratio of IC50 for antiviral activity against darunavir resistant HIV1 P30 harboring protease L10I/I15V/K20R/L24I/V32I/M36I/ M46L/L63P/K70Q/V82A/I84V/L89M mutant infected in human MT4 cells to IC50 for antiviral activity against wild-type HIV1 NL4-3 | 4 | cell-based format | Scientific Literature |
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