# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4380411 | B | Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells using NleTDY-pNA as substrate assessed as cleavage of pNA at pH 7.2 and 298 K by spectrophotometry analysis | Homo sapiens | 23 | ALA4376864 | cell-based format | Scientific Literature | |
2. | ALA4380412 | B | Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate at pH 7.2 and 298 K measured every 60 secs for 600 secs | Homo sapiens | 11 | ALA4376864 | single protein format | Scientific Literature | |
3. | ALA4380413 | B | Inhibition of human chymotrypsin using Suc-AAPF-MCA as substrate at pH 8 and 298 K measured every 60 secs for 600 secs | Homo sapiens | 11 | ALA4376864 | protein format | Scientific Literature | |
4. | ALA4380423 | B | Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells assessed as decrease in angiotensin 1 cleavage to angiotensin 2 at 50 nM incubated for 120 mins at 298 K by UPLC-MS analysis relative to control | Homo sapiens | 1 | ALA4376864 | cell-based format | Scientific Literature | |
5. | ALA4380424 | B | Inhibition of recombinant human chymase expressed in Pichia pastoris X-33 cells assessed as decrease in angiotensin 1 cleavage to angiotensin 2 incubated for 120 mins at 298 K by UPLC-MS analysis | Homo sapiens | 3 | ALA4376864 | cell-based format | Scientific Literature |