The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
The page will load shortly, Thanks for your patience!
# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4431153 B Inhibition of recombinant sPLA2-2A (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins followed by substrate addition measured after 60 mins by colorimetric method Homo sapiens 12 ALA4428134 single protein format Scientific Literature 2. ALA4431154 B Inhibition of sPLA2 in human plasma using 1-Hexadecanoyl-2-(1-pyrenedecanoyl)-sn-glycero-3-phosphomethanol as substrate preincubated for 10 mins followed by substrate addition measured after 90 mins by fluorescence assay Homo sapiens 11 ALA4428134 cell-free format Scientific Literature 3. ALA4431156 B Inhibition of recombinant sPLA2-5 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins followed by substrate addition measured after 60 mins by colorimetric method Homo sapiens 11 ALA4428134 assay format Scientific Literature 4. ALA4431157 B Inhibition of recombinant sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins followed by substrate addition measured after 60 mins by colorimetric method Homo sapiens 11 ALA4428134 single protein format Scientific Literature 5. ALA4431162 A Intrinsic clearance in human hepatocytes at 1 uM assessed per million cells measured up to 60 mins Homo sapiens 6 ALA4428134 cell-based format Scientific Literature 6. ALA4431176 B Inhibition of human OATP1B1 expressed in HEK293 cells assessed as reduction in pivastatin uptake at 25 uM Homo sapiens 2 ALA4428134 cell-based format Scientific Literature 7. ALA4431183 A AUC (0 to infinity) in mouse at 50 umol/kg, po Mus musculus 1 ALA4428134 assay format Scientific Literature 8. ALA4431184 A Clearance in mouse at 10 umol/kg, iv or 50 umol/kg, po Mus musculus 1 ALA4428134 organism-based format Scientific Literature 9. ALA4431185 A Volume of distribution at steady state in mouse at 10 umol/kg, iv or 50 umol/kg, po Mus musculus 1 ALA4428134 organism-based format Scientific Literature 10. ALA4431186 A Oral bioavailability in mouse at 50 umol/kg Mus musculus 1 ALA4428134 organism-based format Scientific Literature 11. ALA4431187 A AUC (0 to infinity) in Sprague-Dawley rat at 8 umol/kg, po Rattus norvegicus 1 ALA4428134 assay format Scientific Literature 12. ALA4431188 A Clearance in Sprague-Dawley rat at 2 umol/kg, iv or 8 umol/kg, po Rattus norvegicus 1 ALA4428134 organism-based format Scientific Literature 13. ALA4431189 A Volume of distribution at steady state in Sprague-Dawley rat at 2 umol/kg, iv or 8 umol/kg, po Rattus norvegicus 1 ALA4428134 organism-based format Scientific Literature 14. ALA4431190 A Oral bioavailability in Sprague-Dawley rat at 8 umol/kg Rattus norvegicus 1 ALA4428134 organism-based format Scientific Literature 15. ALA4431191 A AUC (0 to infinity) in beagle dog at 3 umol/kg, po Canis lupus familiaris 1 ALA4428134 assay format Scientific Literature 16. ALA4431192 A Clearance in beagle dog at 1 umol/kg, iv or 3 umol/kg, po Canis lupus familiaris 1 ALA4428134 organism-based format Scientific Literature 17. ALA4431193 A Volume of distribution at steady state in beagle dog at 1 umol/kg, iv or 3 umol/kg, po Canis lupus familiaris 1 ALA4428134 organism-based format Scientific Literature 18. ALA4431194 A Oral bioavailability in beagle dog at 3 umol/kg Canis lupus familiaris 1 ALA4428134 organism-based format Scientific Literature 19. ALA4431195 A AUC (0 to infinity) in cynomolgus monkey at 15.8 umol/kg, po Macaca fascicularis 1 ALA4428134 assay format Scientific Literature 20. ALA4431196 A Clearance in cynomolgus monkey at 5 umol/kg, iv or 15.8 umol/kg, po Macaca fascicularis 1 ALA4428134 organism-based format Scientific Literature