# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4382091 | Binding | Protac activity at CRBN/BCR-ABL in human K562 cells assessed as reduction in BCR-ABL protein levels at 500 nM incubated for 36 hrs by Western blot analysis | Homo sapiens | 1 | ALA4376901 | cell-based format | Scientific Literature | |
2. | ALA4382092 | Binding | Protac activity at CRBN/ABL in human K562 cells assessed as reduction in ABL protein levels at 500 nM incubated for 36 hrs by Western blot analysis | Homo sapiens | 1 | ALA4376901 | cell-based format | Scientific Literature | |
3. | ALA4382097 | Binding | Protac activity at CRBN/BCR-ABL in human K562 cells assessed as reduction in BCR-ABL protein levels at 250 nM incubated for 32 hrs by Western blot analysis | Homo sapiens | 2 | ALA4376901 | cell-based format | Scientific Literature | |
4. | ALA4382098 | Binding | Protac activity at CRBN/ABL in human K562 cells assessed as reduction in ABL protein levels at 250 nM incubated for 32 hrs by Western blot analysis | Homo sapiens | 2 | ALA4376901 | cell-based format | Scientific Literature | |
5. | ALA4382102 | Binding | Protac activity at CRBN/BCR-ABL in human K562 cells assessed as reduction in BCR-ABL protein levels incubated for 24 hrs followed by exposure to white light up to 24 hrs hrs by Western blot analysis | Homo sapiens | 2 | ALA4376901 | cell-based format | Scientific Literature | |
6. | ALA4382103 | Binding | Protac activity at CRBN/ABL in human K562 cells assessed as reduction in ABL protein levels incubated for 24 hrs followed by exposure to white light up to 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA4376901 | cell-based format | Scientific Literature |