# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4480340 | B | Displacement of ovine [125I-Tyr0]-CRF from human CRF1 receptor expressed in CHO cell membrane measured after 1.5 hrs by TopCount method | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
2. | ALA4480341 | B | Antagonist activity at human CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-stimulated adenylate cyclase activity measured after 4 hrs by Steady-Glo luciferase assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4480342 | B | Displacement of ovine [125I-Tyr0]-CRF from mouse CRF1 receptor in frontal cortex at 20 mg/kg, po measured after 1 hr by gamma scintillation counter method relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
4. | ALA4480343 | B | Displacement of ovine [125I-Tyr0]-CRF from mouse CRF1 receptor in olfactory bulb at 20 mg/kg, po measured after 1 hr by gamma scintillation counter method relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
5. | ALA4480344 | B | Displacement of ovine [125I-Tyr0]-CRF from mouse CRF1 receptor in pituitary gland at 20 mg/kg, po measured after 1 hr by gamma scintillation counter method relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
6. | ALA4480345 | A | Metabolic stability in mouse | Mus musculus | 1 | organism-based format | Scientific Literature |