# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4476933 | B | Inhibition of C-terminal FLAG-6x-His epitope tagged and N-terminal human RAGE signal sequence tagged human BMP1 (23 to 721 amino acids) expressed in CHO-E1 cells pre-incubated for 10 mins before promyostatin peptide substrate addition and measured after 60 mins using 0.5 nM BMP1 by FRET based assay | Homo sapiens | 148 | cell-based format | Patent Bioactivity Data | ||
2. | ALA4476934 | B | Inhibition of C-terminal FLAG-6x-His epitope tagged and N-terminal human RAGE signal sequence tagged human BMP1 (23 to 721 amino acids) expressed in CHO-E1 cells pre-incubated for 10 mins before promyostatin peptide substrate addition and measured after 30 mins using 50 nM BMP1 by FRET based assay | Homo sapiens | 146 | cell-based format | Patent Bioactivity Data | ||
3. | ALA4476935 | B | Inhibition of recombinant human TLL1 I156V/N221S/V284A mutant expressed in CHOE1A cells pre-incubated for 10 mins before promyostatin peptide substrate addition and measured after 60 mins by FRET based assay | Homo sapiens | 141 | cell-based format | Patent Bioactivity Data | ||
4. | ALA4476936 | B | Inhibition of C-terminal Avi-6x-His epitope tagged and N-terminal human RAGE signal sequence tagged recombinant human TLL2 (26 to 1015 amino acids) expressed in CHOE1A cells incubated for 60 mins with promyostatin peptide substrate by FRET based assay | Homo sapiens | 139 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4476937 | F | Reduction in PICP levels in human cardiac fibroblasts incubated for 24 to 48 hrs by ELISA | Homo sapiens | 112 | assay format | Patent Bioactivity Data | ||
6. | ALA4476938 | F | Reduction in mature collagen deposition levels in human cardiac fibroblasts incubated for 24 to 48 hrs by immunostaining based assay | Homo sapiens | 27 | assay format | Patent Bioactivity Data |