# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4416546 | B | Inhibition of human FAAH expressed in baculovirus infected Sf9 cells using N-(6-methoxypyridin-3-yl)octanamide as substrate measured for 15 mins by fluorescence based assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
2. | ALA4416547 | F | Antiallergic activity in rat RBL2H3 cells assessed as inhibition of DNP-HSA-mediated degranulation by measuring decrease in beta-hexosaminidase activity preincubated for 30 mins followed by DNP-HSA stimulation and measured after 30 mins by 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside substrate based assay | Rattus norvegicus | 63 | cell-based format | Scientific Literature | ||
3. | ALA4416548 | F | Antiallergic activity in BALB/c mouse assessed as reduction in anti-DNP-IgE-mediated passive cutaneous anaphylaxis at 1000 mg/kg, po administered once daily for 5 days followed by anti-DNP-IgE stimulation on day 4 and subsequent DNP-HSA challenge on day 5 post 1 hr compound dose and measured after 30 mins by Evans blue dye-based spectrophotometric method relative to control | Mus musculus | 15 | organism-based format | Scientific Literature | ||
4. | ALA4416549 | A | Substrate activity at human FAAH expressed in baculovirus infected Sf9 cells assessed as docosahexaenoic acid formation incubated for 60 mins by HPLC analysis | Homo sapiens | 16 | cell-based format | Scientific Literature |