| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4401249 | B | Inhibition of CMFDA binding to human N-terminal 6x-His-tagged GSTO1-1 preincubated for 30 mins followed by CMFDA addition and measured after 30 mins by in-gel fluorescence binding assay | Homo sapiens | 44 | single protein format | Scientific Literature | ||
| 2. | ALA4401250 | F | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
| 3. | ALA4401251 | F | Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
| 4. | ALA4401252 | A | Metabolic stability in mouse liver microsomes at 1 uM in presence of NADPH incubated for 0 mins by LC-MS/MS analysis | Mus musculus | 3 | microsome format | Scientific Literature | ||
| 5. | ALA4401253 | A | Metabolic stability in human liver microsomes at 1 uM in presence of NADPH incubated for 0 mins by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 6. | ALA4401254 | P | Stability of the compound in 20% acetonitrile/PBS buffer at room temperature by LC-MS/MS analysis | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA4401255 | B | Inhibition of CMFDA binding to human N-terminal 6x-His-tagged GSTO1-1 at 10 uM preincubated for 30 mins followed by CMFDA addition and measured after 30 mins in presence of 1 to 10 uM MgCl2 by in-gel fluorescence binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4401256 | B | Inhibition of CMFDA binding to human N-terminal 6x-His-tagged GSTO1-1 at 10 uM preincubated for 30 mins followed by CMFDA addition and measured after 30 mins in presence of 1 to 10 uM CuSO4 by in-gel fluorescence binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4401257 | B | Inhibition of CMFDA binding to human N-terminal 6x-His-tagged GSTO1-1 at 10 uM preincubated for 30 mins followed by CMFDA addition and measured after 30 mins in presence of 1 to 10 uM FeCl3 by in-gel fluorescence binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4401258 | B | Inhibition of CMFDA binding to human N-terminal 6x-His-tagged GSTO1-1 at 10 uM preincubated for 30 mins followed by CMFDA addition and measured after 30 mins in presence of 1 to 10 uM KCl by in-gel fluorescence binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4401259 | B | Inhibition of CMFDA binding to human N-terminal 6x-His-tagged GSTO1-1 at 10 uM preincubated for 30 mins followed by CMFDA addition and measured after 30 mins in presence of 10 uM MnCl2 by in-gel fluorescence binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4401260 | B | Inhibition of CMFDA binding to human N-terminal 6x-His-tagged GSTO1-1 at 10 uM preincubated for 30 mins followed by CMFDA addition and measured after 30 mins in presence of 10 uM ZnCl2 by in-gel fluorescence binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4401261 | B | Inhibition of CMFDA binding to human N-terminal 6x-His-tagged GSTO1-1 assessed as reduction in reduction of 4-NPG to 4-nitroacetophenone at 0.00001 to 1 uM incubated for 30 mins by 4NPG reductase assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4401262 | A | Metabolic stability in mouse liver microsomes at 1 uM in presence of NADPH incubated for 5 mins by LC-MS/MS analysis | Mus musculus | 3 | microsome format | Scientific Literature | ||
| 15. | ALA4401263 | A | Metabolic stability in mouse liver microsomes at 1 uM in presence of NADPH incubated for 10 mins by LC-MS/MS analysis | Mus musculus | 3 | microsome format | Scientific Literature | ||
| 16. | ALA4401264 | A | Metabolic stability in mouse liver microsomes at 1 uM in presence of NADPH incubated for 15 mins by LC-MS/MS analysis | Mus musculus | 3 | microsome format | Scientific Literature | ||
| 17. | ALA4401265 | A | Metabolic stability in mouse liver microsomes at 1 uM in presence of NADPH incubated for 30 mins by LC-MS/MS analysis | Mus musculus | 2 | microsome format | Scientific Literature | ||
| 18. | ALA4401266 | A | Metabolic stability in mouse liver microsomes at 1 uM in presence of NADPH incubated for 45 mins by LC-MS/MS analysis | Mus musculus | 2 | microsome format | Scientific Literature | ||
| 19. | ALA4401267 | A | Metabolic stability in mouse liver microsomes at 1 uM in presence of NADPH incubated for 60 mins by LC-MS/MS analysis | Mus musculus | 2 | microsome format | Scientific Literature | ||
| 20. | ALA4401268 | A | Half life in mouse liver microsomes at 1 uM in presence of NADPH by LC-MS/MS analysis | Mus musculus | 3 | microsome format | Scientific Literature |
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