#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5121788	Binding	Inhibition of FGFR (unknown origin) at 200 nM in presence of ATP at Km concentration by mobility shift assay relative to control	Homo sapiens	1	ALA5120772	protein format	Scientific Literature
2.	ALA5121789	ADME	AUC (0 to 24 hrs) in Beagle dog at 1 mg/kg, po measured upto 72 hrs by LC-MS/MS analysis	Canis lupus familiaris	1	ALA5120772	organism-based format	Scientific Literature
3.	ALA5121790	Toxicity	Cytotoxicity against mouse NIH/3T3 cells overexpressing FGFR3 S249C assessed as cell growth inhibition incubated for 5 days by CellTitre-Glo assay	Mus musculus	14	ALA5120772	cell-based format	Scientific Literature
4.	ALA5121791	ADME	Intrinsic clearance in human liver microsomes	Homo sapiens	15	ALA5120772	microsome format	Scientific Literature
5.	ALA5121792	Toxicity	Inhibition of hERG channel expressed in CHO cells at -80 mV holding potential by Qpatch clamp method	Homo sapiens	13	ALA5120772	cell-based format	Scientific Literature
6.	ALA5121793	Physicochemical	Lipophilicity, logD of the compound in 1-octanol and phosphate buffer at pH 7.4 by LC-MS analysis		14	ALA5120772	small-molecule physicochemical format	Scientific Literature
7.	ALA5121794	ADME	Permeability of the compound in aqueous buffer at pH 6.5 incubated for 2 hrs by PAMPA based HPLC analysis		14	ALA5120772	assay format	Scientific Literature
8.	ALA5121795	ADME	Plasma concentration in ICR mouse at 30 mg/kg, po measured after 6 hrs of administration by LC-MS/MS analysis	Mus musculus	4	ALA5120772	organism-based format	Scientific Literature
9.	ALA5121796	Functional	Invivo inhibition of FGFR3 phosphorylation in human NIH/3T3 cells overexpressing FGFR3 S249C xenografted in Balb/c nude mouse at 30 mg/kg, po administered as single dose and measured after 6 hrs by sandwich ELISA analysis relative to control	Mus musculus	4	ALA5120772	organism-based format	Scientific Literature
10.	ALA5121797	ADME	Tmax in Beagle dog at 1 mg/kg, po measured upto 72 hrs by LC-MS/MS analysis	Canis lupus familiaris	1	ALA5120772	organism-based format	Scientific Literature
11.	ALA5121798	ADME	Cmax in Beagle dog at 1 mg/kg, po measured upto 72 hrs by LC-MS/MS analysis	Canis lupus familiaris	1	ALA5120772	organism-based format	Scientific Literature
12.	ALA5121799	ADME	Tmax in Beagle dog at 10 mg/kg, po measured upto 72 hrs by LC-MS/MS analysis	Canis lupus familiaris	1	ALA5120772	organism-based format	Scientific Literature
13.	ALA5121800	ADME	Tmax in Beagle dog at 100 mg/kg, po measured upto 72 hrs by LC-MS/MS analysis	Canis lupus familiaris	1	ALA5120772	organism-based format	Scientific Literature
14.	ALA5121801	ADME	Cmax in Beagle dog at 10 mg/kg, po measured upto 72 hrs by LC-MS/MS analysis	Canis lupus familiaris	1	ALA5120772	organism-based format	Scientific Literature
15.	ALA5121802	ADME	Cmax in Beagle dog at 100 mg/kg, po measured upto 72 hrs by LC-MS/MS analysis	Canis lupus familiaris	1	ALA5120772	organism-based format	Scientific Literature
16.	ALA5121803	ADME	AUC (0 to 24 hrs) in Beagle dog at 10 mg/kg, po measured upto 72 hrs by LC-MS/MS analysis	Canis lupus familiaris	1	ALA5120772	organism-based format	Scientific Literature
17.	ALA5121804	ADME	AUC (0 to 24 hrs) in Beagle dog at 100 mg/kg, po measured upto 72 hrs by LC-MS/MS analysis	Canis lupus familiaris	1	ALA5120772	organism-based format	Scientific Literature
18.	ALA5121805	Toxicity	Toxicity in Beagle dog assessed as vomiting at 1 mg/kg, po administered for 7 days and measured after 24 hrs post last dose by telemetry study	Canis lupus familiaris	1	ALA5120772	organism-based format	Scientific Literature
19.	ALA5121806	Toxicity	Toxicity in Beagle dog assessed as color change in feces at 1 to 10 mg/kg, po administered for 7 days and measured after 24 hrs post last dose by telemetry study	Canis lupus familiaris	1	ALA5120772	organism-based format	Scientific Literature
20.	ALA5121807	Toxicity	Toxicity in Beagle dog assessed as systolic blood pressure at 1 mg/kg, po administered for 7 days and measured after 8 hrs post last dose by telemetry study	Canis lupus familiaris	1	ALA5120772	organism-based format	Scientific Literature