#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5120624	Binding	Inhibition of JAK1/JAK3 in human primary T-cells assessed as reduction of IL-2 stimulated STAT5 phosphorylation preincubated for 1 hr followed by IL-2 stimulation for 15 mins by FACS method	Homo sapiens	33	ALA5113550	cell-based format	Scientific Literature
2.	ALA5120628	Functional	Inhibition of IL-2 stimulated IFN-gamma production in BALB/c mouse at 40 mg/kg, po pretreated for 30 mins followed by IL-2 stimulation and measured after 4 hrs by ELISA	Mus musculus	15	ALA5113550	organism-based format	Scientific Literature
3.	ALA5120629	Toxicity	Inhibition of JAK2 signaling pathway in human CHEP cells assessed as inhibition of EPO-induced cell survival preincubated for 1 hr followed by EPO addition and measured after 48 hrs by CellTiter-Glo luminescent assay	Homo sapiens	12	ALA5113550	cell-based format	Scientific Literature
4.	ALA5120630	Binding	Selectivity ratio of IC50 for inhibition of JAK2 signaling pathway in EPO-stimulated human CHEP cells to IC50 for inhibition of JAK1/JAK3 in human primary T-cells assessed as reduction of IL-2 stimulated STAT5 phosphorylation	Homo sapiens	12	ALA5113550	assay format	Scientific Literature
5.	ALA5120631	Functional	Inhibition of IL-2 stimulated IFN-gamma production in BALB/c mouse at 5 mg/kg, po pretreated for 30 mins followed by IL-2 stimulation and measured after 4 hrs by ELISA	Mus musculus	6	ALA5113550	organism-based format	Scientific Literature
6.	ALA5120632	ADME	Inhibition of CYP3A4 (unknown origin) in absence of NADPH	Homo sapiens	11	ALA5113550	single protein format	Scientific Literature
7.	ALA5120633	ADME	Inhibition of CYP3A4 (unknown origin) in presence of NADPH	Homo sapiens	11	ALA5113550	single protein format	Scientific Literature
8.	ALA5120634	ADME	Inhibition of CYP1A2 (unknown origin)	Homo sapiens	2	ALA5113550	single protein format	Scientific Literature
9.	ALA5120635	ADME	Inhibition of CYP2D6 (unknown origin)	Homo sapiens	2	ALA5113550	single protein format	Scientific Literature
10.	ALA5120636	ADME	Inhibition of CYP2C19 (unknown origin)	Homo sapiens	2	ALA5113550	single protein format	Scientific Literature
11.	ALA5120637	Binding	Inhibition of human recombinant GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system by Z'-lyte assay	Homo sapiens	1	ALA5113550	assay format	Scientific Literature
12.	ALA5120638	Toxicity	Inhibition of human recombinant GST-tagged JAK2 catalytic domain (809 to 1153 residues) expressed in baculovirus expression system by Z'-lyte assay	Homo sapiens	1	ALA5113550	assay format	Scientific Literature
13.	ALA5120639	Binding	Inhibition of human recombinant GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system by Z'-lyte assay	Homo sapiens	1	ALA5113550	assay format	Scientific Literature
14.	ALA5120640	Binding	Inhibition of human recombinant N-terminal GST-tagged TYK2 (833 to 1187 residues) expressed in baculovirus expression system by Z'-lyte assay	Homo sapiens	1	ALA5113550	assay format	Scientific Literature
15.	ALA5120641	Binding	Inhibition of JAK1/JAK3 signaling pathway in human primary T-cells assessed as reduction of IL-2 induced cell proliferation	Homo sapiens	1	ALA5113550	cell-based format	Scientific Literature
16.	ALA5120642	Binding	Inhibition of JAK1/TYK2 signaling pathway in human primary T-cells assessed as reduction of IFN-alpha induced STAT1 phosphorylation	Homo sapiens	1	ALA5113550	cell-based format	Scientific Literature
17.	ALA5120643	Toxicity	Inhibition of JAK2 signaling pathway in human UKE-1 cells assessed as reduction of cell proliferation	Homo sapiens	1	ALA5113550	cell-based format	Scientific Literature
18.	ALA5120644	Binding	Inhibition of JAK2/TYK2 signaling pathway in human primary T-cells assessed as reduction of IL-12 induced STAT4 phosphorylation	Homo sapiens	1	ALA5113550	cell-based format	Scientific Literature
19.	ALA5120645	Binding	Inhibition of JAK1/JAK2 signaling pathway in human U-937 cells assessed as reduction of IFN-gamma induced ICAM1 expression	Homo sapiens	1	ALA5113550	cell-based format	Scientific Literature
20.	ALA5120646	Functional	Inhibition of IL-2 stimulated IFN-gamma production in BALB/c mouse at 20 mg/kg, po pretreated for 30 mins followed by IL-2 stimulation and measured after 4 hrs by ELISA	Mus musculus	1	ALA5113550	organism-based format	Scientific Literature