# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5155325 | Binding | Inhibition of human recombinant Cathepsin L assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assay | Homo sapiens | 5 | ALA5154645 | single protein format | Scientific Literature | |
2. | ALA5155326 | Binding | Inhibition of human recombinant Cathepsin B assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assay | Homo sapiens | 5 | ALA5154645 | single protein format | Scientific Literature | |
3. | ALA5155327 | Binding | Inhibition of human recombinant Cathepsin V assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assay | Homo sapiens | 5 | ALA5154645 | single protein format | Scientific Literature | |
4. | ALA5155328 | Binding | Inhibition of human recombinant Cathepsin S assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assay | Homo sapiens | 5 | ALA5154645 | single protein format | Scientific Literature | |
5. | ALA5155329 | Binding | Inhibition of human recombinant Cathepsin K assessed remaining activity using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assay | Homo sapiens | 5 | ALA5154645 | single protein format | Scientific Literature | |
6. | ALA5155330 | Functional | Antiviral activity against SARS-CoV-2 infected in African green monkey Vero E6 cells assessed as inhibition of viral infection pre incubated for 30 minutes followed by viral infection and measured after 72 hrs by Nucblue dye based fluorometric analysis | Severe acute respiratory syndrome coronavirus 2 | 5 | ALA5154645 | organism-based format | Scientific Literature | |
7. | ALA5155331 | Binding | Inhibition of human recombinant Cathepsin L assessed as Kinact using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assay | Homo sapiens | 5 | ALA5154645 | single protein format | Scientific Literature | |
8. | ALA5155332 | Binding | Inhibition of human recombinant Cathepsin B assessed as Kinact using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assay | Homo sapiens | 5 | ALA5154645 | single protein format | Scientific Literature | |
9. | ALA5155333 | Binding | Inhibition of mouse Cathepsin L assessed as Kinact using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assay | Mus musculus | 5 | ALA5154645 | single protein format | Scientific Literature | |
10. | ALA5155334 | Binding | Inhibition of human recombinant Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assay | Homo sapiens | 5 | ALA5154645 | single protein format | Scientific Literature | |
11. | ALA5155335 | Binding | Inhibition of human recombinant Cathepsin B assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assay | Homo sapiens | 5 | ALA5154645 | single protein format | Scientific Literature | |
12. | ALA5155336 | Binding | Inhibition of mouse Cathepsin L assessed as Apparent inhibition constant using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assay | Mus musculus | 5 | ALA5154645 | single protein format | Scientific Literature | |
13. | ALA5155337 | Binding | Inhibition of human recombinant Cathepsin L assessed as ratio of Kinact/Kiapp using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assay | Homo sapiens | 5 | ALA5154645 | single protein format | Scientific Literature | |
14. | ALA5155338 | Binding | Inhibition of human recombinant Cathepsin B assessed as ratio of Kinact/Kiapp using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assay | Homo sapiens | 5 | ALA5154645 | single protein format | Scientific Literature | |
15. | ALA5155339 | Binding | Inhibition of mouse Cathepsin L assessed as ratio of Kinact/Kiapp using Z-FR-AMC as substrate inubated for 30 mins by fluorometric assay | Mus musculus | 5 | ALA5154645 | single protein format | Scientific Literature | |
16. | ALA5155340 | Toxicity | Cytotoxicity against cells African green monkey Vero E6 cells incubated for 24 to 72 hrs by alamar blue assay | Chlorocebus sabaeus | 5 | ALA5154645 | cell-based format | Scientific Literature | |
17. | ALA5159488 | Binding | Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by fluorimetric analysis | Trypanosoma cruzi | 25 | ALA5154751 | single protein format | Scientific Literature | |
18. | ALA5159489 | Functional | Antitrypanosomal activity against amastigotes form of Trypanosoma cruzi CA-I/72 infected in mouse C2C12 cells assessed as parasite infection level by DAPI staining based microscopic analysis | Trypanosoma cruzi | 24 | ALA5154751 | organism-based format | Scientific Literature | |
19. | ALA5159490 | Toxicity | Cytotoxicity against mouse C2C12 cells assessed as lethal dose | Mus musculus | 26 | ALA5154751 | cell-based format | Scientific Literature |