# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4629227 | A | Prodrug activation assessed as PSA-mediated (unknown origin) compound cleavage measured up to 8 hrs by HPLC analysis | Homo sapiens | 1 | ALA4627365 | single protein format | Scientific Literature | |
2. | ALA4629228 | A | Prodrug activation assessed as PSA-mediated (unknown origin) 4-((R)-2-((R)-2-amino-3-hydroxypropanamido)-4-methylpentanamido)benzyl diethyl-carbamodithioate metabolite formation by HPLC analysis | Homo sapiens | 1 | ALA4627365 | single protein format | Scientific Literature | |
3. | ALA4629229 | A | Prodrug activation assessed as PSA-mediated (unknown origin) diethyldithiocarbamate formation in presence of leucine aminopeptidase by LC-MS analysis | Homo sapiens | 2 | ALA4627365 | single protein format | Scientific Literature | |
4. | ALA4629230 | A | Prodrug activation assessed as PSA-mediated (unknown origin) Cu(diethyldithiocarbamate)2 complex formation in presence of leucine aminopeptidase and CuSO4 after 14.5 mins by LC-MS analysis | Homo sapiens | 2 | ALA4627365 | single protein format | Scientific Literature | |
5. | ALA4629233 | A | Prodrug activation in human LNCAP cell lysates assessed as PSA-mediated peptide cleavage measured up to 4 hrs by HPLC analysis | Homo sapiens | 2 | ALA4627365 | subcellular format | Scientific Literature | |
6. | ALA4629234 | A | Prodrug activation in human PC3 cell lysate assessed as peptide cleavage measured up to 4 hrs by HPLC analysis | Homo sapiens | 1 | ALA4627365 | subcellular format | Scientific Literature | |
7. | ALA4629236 | F | Antiproliferative activity against human LNCAP cells assessed as reduction in cell viability after 24 hrs in presence of 1 uM CuSO4 by resazurin dye based assay | Homo sapiens | 2 | ALA4627365 | cell-based format | Scientific Literature | |
8. | ALA4629237 | A | Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 24 hrs in presence of CuSO4 by resazurin dye based assay | Homo sapiens | 2 | ALA4627365 | cell-based format | Scientific Literature |