# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4612120 | P | Stability of the compound in pH 7.4 potassium phosphate buffer assessed as compound hydrolysis after 48 hrs | 15 | ALA4610093 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA4612121 | B | Inhibition of bovine brain tubulin polymerisation preincubated for 15 mins followed by GTP addition and measured for 20 mins by turbidimetry based spectrophotometric method | Bos taurus | 18 | ALA4610093 | assay format | Scientific Literature | |
3. | ALA4612122 | B | Inhibition of [3H]colchicine binding to tubulin (unknown origin) at 1 uM incubated for 10 mins by scintillation counting relative to control | Homo sapiens | 6 | ALA4610093 | protein complex format | Scientific Literature | |
4. | ALA4612123 | B | Inhibition of [3H]colchicine binding to tubulin (unknown origin) at 5 uM incubated for 10 mins by scintillation counting relative to control | Homo sapiens | 13 | ALA4610093 | protein complex format | Scientific Literature | |
5. | ALA4612127 | B | Substrate activity at rat NADPH-cytochrome P450 oxidoreductase expressed in supersomes assessed as compound cleavage after 90 mins in anaerobic condition by HPLC analysis | Rattus norvegicus | 15 | ALA4610093 | assay format | Scientific Literature | |
6. | ALA4612128 | F | Cytotoxicity against human A549 cells incubated for 52 hrs in oxic condition by sulforhodamine B assay | Homo sapiens | 21 | ALA4610093 | cell-based format | Scientific Literature | |
7. | ALA4612129 | F | Cytotoxicity against human A549 cells incubated for 4 hrs in anoxic condition followed by oxic exposure for 48 hrs by sulforhodamine B assay | Homo sapiens | 21 | ALA4610093 | cell-based format | Scientific Literature | |
8. | ALA4612130 | F | Ratio of GI50 for human A549 cells in oxic condition to GI50 for anoxic condition | Homo sapiens | 17 | ALA4610093 | cell-based format | Scientific Literature | |
9. | ALA4612139 | P | Drug metabolism assessed as cyclization to (Z)-4-Methoxy-2-methyl-2-(5-nitrothiophen-2-yl)-7-(3,4,5-trimethoxystyryl)benzo[d][1,3]dioxole | 2 | ALA4610093 | small-molecule physicochemical format | Scientific Literature |