# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4630224 | B | Inhibition of human NaV1.3 at 100 uM | Homo sapiens | 2 | ALA4627405 | single protein format | Scientific Literature | |
2. | ALA4630225 | B | Inhibition of human NaV1.2 at 100 uM | Homo sapiens | 2 | ALA4627405 | single protein format | Scientific Literature | |
3. | ALA4630226 | F | Antagonist activity at N-terminal HA-tagged and C-terminal FLAG-tagged human MC4R expressed in HEK293 cells assessed as reduction in alpha-MSH-induced cAMP accumulation at 100 uM incubated for 3 hrs by luciferase reporter gene assay | Homo sapiens | 2 | ALA4627405 | cell-based format | Scientific Literature | |
4. | ALA4630227 | B | Inhibition of human NaV1.1 at 100 uM | Homo sapiens | 2 | ALA4627405 | single protein format | Scientific Literature | |
5. | ALA4630228 | F | Activity at N-terminal HA-tagged and C-terminal FLAG-tagged human MC1R expressed in HEK293 cells assessed as potentiation of alpha-MSH-induced cAMP accumulation at 100 uM incubated for 3 hrs by luciferase reporter gene assay | Homo sapiens | 2 | ALA4627405 | cell-based format | Scientific Literature | |
6. | ALA4630230 | F | Agonist activity at human MC4R expressed in HEK293 cells assessed as stimulation of cAMP accumulation at 100 uM incubated for 3 hrs by luciferase reporter gene assay | Homo sapiens | 2 | ALA4627405 | cell-based format | Scientific Literature | |
7. | ALA4630231 | F | Agonist activity at N-terminal HA-tagged and C-terminal FLAG-tagged human MC1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation at 100 uM incubated for 3 hrs by luciferase reporter gene assay | Homo sapiens | 2 | ALA4627405 | cell-based format | Scientific Literature | |
8. | ALA4630232 | F | Effect on cAMP production in HEK293 cells at 100 uM incubated for 3 hrs by luciferase reporter gene assay | Homo sapiens | 2 | ALA4627405 | cell-based format | Scientific Literature | |
9. | ALA4630233 | B | Displacement of [125I]-NDP-alpha-MSH from human MC5R expressed in CHO-K1 cell membranes incubated for 3 hrs by top-count beta counting | Homo sapiens | 2 | ALA4627405 | cell-based format | Scientific Literature | |
10. | ALA4630234 | B | Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in CHO-K1 cell membranes incubated for 3 hrs by top-count beta counting | Homo sapiens | 2 | ALA4627405 | cell-based format | Scientific Literature | |
11. | ALA4630235 | B | Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in CHO-K1 cell membranes incubated for 3 hrs by top-count beta counting | Homo sapiens | 2 | ALA4627405 | cell-based format | Scientific Literature | |
12. | ALA4630236 | B | Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in CHO-K1 cell membranes incubated for 3 hrs by top-count beta counting | Homo sapiens | 2 | ALA4627405 | cell-based format | Scientific Literature | |
13. | ALA4630237 | B | Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in CHO-K1 cell membranes incubated for 3 hrs by top-count beta counting relative to control | Homo sapiens | 2 | ALA4627405 | cell-based format | Scientific Literature | |
14. | ALA4630238 | B | Inhibition of human NaV1.4 at 100 uM | Homo sapiens | 2 | ALA4627405 | single protein format | Scientific Literature | |
15. | ALA4630239 | B | Inhibition of human NaV1.5 at 100 uM | Homo sapiens | 2 | ALA4627405 | single protein format | Scientific Literature | |
16. | ALA4630240 | B | Inhibition of human NaV1.6 at 100 uM | Homo sapiens | 2 | ALA4627405 | single protein format | Scientific Literature | |
17. | ALA4630241 | B | Inhibition of human NaV1.7 at 100 uM | Homo sapiens | 2 | ALA4627405 | single protein format | Scientific Literature | |
18. | ALA4630242 | B | Inhibition of human NaV1.8 at 100 uM | Homo sapiens | 2 | ALA4627405 | single protein format | Scientific Literature | |
19. | ALA4630243 | B | Inhibition of human Kv1.1 at 100 uM | Homo sapiens | 2 | ALA4627405 | single protein format | Scientific Literature | |
20. | ALA4630244 | B | Inhibition of human Kv1.2 at 100 uM | Homo sapiens | 2 | ALA4627405 | single protein format | Scientific Literature |