# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4604067 | Functional | Cytotoxicity against human HL60 cells assessed as cell growth inhibition at 5 ug/ml measured after 72 hrs by MTT assay relative to control | Homo sapiens | 9 | ALA4602644 | cell-based format | Scientific Literature | |
2. | ALA4604068 | Functional | Cytotoxicity against human HCT116 cells assessed as cell growth inhibition at 5 ug/ml measured after 72 hrs by MTT assay relative to control | Homo sapiens | 9 | ALA4602644 | cell-based format | Scientific Literature | |
3. | ALA4604069 | Functional | Cytotoxicity against human OVCAR8 cells assessed as cell growth inhibition at 5 ug/ml measured after 72 hrs by MTT assay relative to control | Homo sapiens | 9 | ALA4602644 | cell-based format | Scientific Literature | |
4. | ALA4604070 | Functional | Cytotoxicity against human HL60 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 2 | ALA4602644 | cell-based format | Scientific Literature | |
5. | ALA4604071 | Functional | Cytotoxicity against human K562 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 2 | ALA4602644 | cell-based format | Scientific Literature | |
6. | ALA4604072 | Functional | Cytotoxicity against human SF295 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 2 | ALA4602644 | cell-based format | Scientific Literature | |
7. | ALA4604073 | Functional | Cytotoxicity against human HCT116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 2 | ALA4602644 | cell-based format | Scientific Literature | |
8. | ALA4604074 | Functional | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 2 | ALA4602644 | cell-based format | Scientific Literature | |
9. | ALA4604075 | Functional | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 2 | ALA4602644 | cell-based format | Scientific Literature | |
10. | ALA4604076 | ADME | Cytotoxicity against mouse L929 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Mus musculus | 2 | ALA4602644 | cell-based format | Scientific Literature | |
11. | ALA4604077 | Functional | Cytotoxicity against human HCT116 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay | Homo sapiens | 2 | ALA4602644 | cell-based format | Scientific Literature | |
12. | ALA4604078 | Functional | Cytotoxicity against human HCT116 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay | Homo sapiens | 2 | ALA4602644 | cell-based format | Scientific Literature | |
13. | ALA4604079 | Functional | Induction of morphological changes in human HCT116 cells assessed as increase in cell size at 1.5 to 6 uM measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4602644 | cell-based format | Scientific Literature | |
14. | ALA4604080 | Functional | Induction of morphological changes in human HCT116 cells assessed as decrease in number of mitotic cells at 1.5 to 6 uM measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4602644 | cell-based format | Scientific Literature | |
15. | ALA4604081 | Functional | Induction of morphological changes in human HCT116 cells assessed as increase in number of intracellular vesicles at 1.5 to 6 uM measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4602644 | cell-based format | Scientific Literature | |
16. | ALA4604082 | Functional | Induction of morphological changes in human HCT116 cells assessed as increase in size of intracellular vesicles at 1.5 to 6 uM measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4602644 | cell-based format | Scientific Literature | |
17. | ALA4604085 | Functional | Induction of morphological changes in human HCT116 cells assessed as discrete apoptotic cells at 6 uM measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA4602644 | cell-based format | Scientific Literature | |
18. | ALA4604086 | Functional | Induction of autophagy in human HCT116 cells assessed as formation of acidic vesicular organelles at 3 to 6 uM measured after 48 hrs by acridine orange staining based confocal microscopy | Homo sapiens | 1 | ALA4602644 | cell-based format | Scientific Literature | |
19. | ALA4604087 | Functional | Induction of autophagy in human HCT116 cells assessed as formation of autophagic vacuoles at 3 to 6 uM measured after 48 hrs by monodansylcadaverine staining based confocal microscopy | Homo sapiens | 1 | ALA4602644 | cell-based format | Scientific Literature | |
20. | ALA4604088 | Functional | Induction of autophagy in human HCT116 cells increase in Beclin 1 level at 3 uM measured after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602644 | cell-based format | Scientific Literature |