| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4619036 | B | Inhibition of recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus infected Sf21 insect cells using PIP2 as substrate after 30 mins in presence of ATP at 2xKm concentration by TR-FRET assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 2. | ALA4619037 | B | Inhibition of human full length p110alpha/p85alpha using PIP2 as substrate after 30 mins in presence of ATP at 2xKm concentration by TR-FRET assay | Homo sapiens | 20 | protein complex format | Scientific Literature | ||
| 3. | ALA4619038 | B | Inhibition of human p110delta catalytic subunit/p85alpha using PIP2 as substrate after 30 mins in presence of ATP at 2xKm concentration by TR-FRET assay | Homo sapiens | 20 | protein complex format | Scientific Literature | ||
| 4. | ALA4619039 | B | Inhibition of human full length p110gamma using PIP2 as substrate after 30 mins in presence of ATP at 2xKm concentration by TR-FRET assay | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 5. | ALA4619040 | B | Selectivity index, ratio of IC50 for human full length p110alpha/p85alpha to IC50 for recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus infected Sf21 insect cells | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 6. | ALA4619041 | B | Selectivity index, ratio of IC50 for human p110delta catalytic subunit/p85alpha to IC50 for recombinant human full-length N-terminal His6-tagged p110beta/human recombinant full-length untagged p85alpha expressed in baculovirus infected Sf21 insect cells | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 7. | ALA4619043 | P | Dissociation constant, acidic pKa of compound | 5 | small-molecule physicochemical format | Scientific Literature | |||
| 8. | ALA4619044 | A | Inhibition of human CYP3A4 | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 9. | ALA4619045 | A | Clearance in human hepatocytes at 1 uM measured up to 250 mins by UHPLC-HRMS analysis | Homo sapiens | 5 | cell-based format | Scientific Literature |
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