# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4606432 | Functional | Antimicrobial activity against Pseudomonas aeruginosa clinical isolates by standard broth microdilution method | Pseudomonas aeruginosa | 5 | ALA4602731 | organism-based format | Scientific Literature | |
2. | ALA4606433 | Functional | Antimicrobial activity against Klebsiella pneumoniae clinical isolates by standard broth microdilution method | Klebsiella pneumoniae | 5 | ALA4602731 | organism-based format | Scientific Literature | |
3. | ALA4606434 | Functional | Antimicrobial activity against Escherichia coli clinical isolates by standard broth microdilution method | Escherichia coli | 4 | ALA4602731 | organism-based format | Scientific Literature | |
4. | ALA4606435 | Functional | Antimicrobial activity against Pseudomonas aeruginosa PAO1 in absence of iron by standard broth microdilution method | Pseudomonas aeruginosa | 3 | ALA4602731 | organism-based format | Scientific Literature | |
5. | ALA4606436 | Functional | Antimicrobial activity against Pseudomonas aeruginosa PAO1 in presence of 0.1 ug/ml iron by standard broth microdilution method | Pseudomonas aeruginosa | 3 | ALA4602731 | organism-based format | Scientific Literature | |
6. | ALA4606437 | Functional | Antimicrobial activity against Pseudomonas aeruginosa PAO1 in presence of 1 ug/ml iron by standard broth microdilution method | Pseudomonas aeruginosa | 3 | ALA4602731 | organism-based format | Scientific Literature | |
7. | ALA4606438 | Functional | Antimicrobial activity against Pseudomonas aeruginosa PAO1 in presence of 10 ug/ml iron by standard broth microdilution method | Pseudomonas aeruginosa | 3 | ALA4602731 | organism-based format | Scientific Literature | |
8. | ALA4606439 | Functional | Antimicrobial activity against Klebsiella pneumoniae clinical isolates in absence of iron by standard broth microdilution method | Klebsiella pneumoniae | 3 | ALA4602731 | organism-based format | Scientific Literature | |
9. | ALA4606440 | Functional | Antimicrobial activity against Klebsiella pneumoniae clinical isolates in presence of 0.1 ug/ml iron by standard broth microdilution method | Klebsiella pneumoniae | 3 | ALA4602731 | organism-based format | Scientific Literature | |
10. | ALA4606441 | Functional | Antimicrobial activity against Klebsiella pneumoniae clinical isolates in presence of 1 ug/ml iron by standard broth microdilution method | Klebsiella pneumoniae | 3 | ALA4602731 | organism-based format | Scientific Literature | |
11. | ALA4606442 | Functional | Antimicrobial activity against Klebsiella pneumoniae clinical isolates in presence of 10 ug/ml iron by standard broth microdilution method | Klebsiella pneumoniae | 3 | ALA4602731 | organism-based format | Scientific Literature | |
12. | ALA4606443 | Physicochemical | Solubility in pH 7.5 phosphate buffer by nephelometry | 1 | ALA4602731 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA4606444 | Physicochemical | Stability in pH 7.5 phosphate buffer assessed as compound hydrolysis after 2 weeks at room temperature | 1 | ALA4602731 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA4606446 | ADME | Permeability in human Caco2 cells | Homo sapiens | 1 | ALA4602731 | cell-based format | Scientific Literature | |
15. | ALA4606447 | ADME | Half life human liver microsomes | Homo sapiens | 1 | ALA4602731 | microsome format | Scientific Literature | |
16. | ALA4606448 | ADME | Half life CD1 mouse liver microsomes | Mus musculus | 1 | ALA4602731 | microsome format | Scientific Literature | |
17. | ALA4606449 | ADME | Inhibition of CYP450 (unknown origin) at 30 uM | Homo sapiens | 1 | ALA4602731 | protein format | Scientific Literature | |
18. | ALA4606450 | ADME | Plasma concentration CD1 mouse at 50 mg/kg, iv after 2 hrs by HPLC-MS/MS analysis | Mus musculus | 1 | ALA4602731 | organism-based format | Scientific Literature | |
19. | ALA4606451 | Toxicity | Toxicity in human primary hepatocytes at 100 uM incubated for 72 hrs | Homo sapiens | 1 | ALA4602731 | cell-based format | Scientific Literature | |
20. | ALA4606452 | Binding | Inhibition of COX1 (unknown origin) at 30 uM relative to control | Homo sapiens | 1 | ALA4602731 | single protein format | Scientific Literature |