# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4623103 | B | Activation of human ESD expressed in HEK293T cells transfected with pEGFP-N1 at 0.1 uM after 24 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA4623104 | B | Activation of ESD in human L02 cells at 0.1 to 1 uM after 24 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4623105 | B | Activation of human ESD expressed in HEK293T cells transfected with pEGFP-N1 assessed as protein redistribution in cytoplasm by fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4623106 | B | Activation of human ESD expressed in HEK293T cells transfected with pEGFP-N1 assessed as compound co-localization with protein by fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA4623107 | B | Inhibition of IgG binding to ESD in human L02 cells by immuno precipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4623108 | B | Binding affinity to human ESD expressed in HEK293T cells assessed as association rate constant | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA4623109 | B | Binding affinity to human ESD expressed in HEK293T cells assessed as dissociation rate constant | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA4623110 | B | Binding affinity to human ESD expressed in HEK293T cells assessed as dissociation constant | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA4623111 | B | Activation of wild type human ESD expressed in HEK293T cells assessed as increase in protein mono ubiquitination at 0.1 to 1 uM incubated for 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4623112 | B | Activation of ESD K180A mutant (unknown origin) expressed in HEK293T cells transfected with p-EGFP assessed as increase in protein mono ubiquitination at 0.1 to 1 uM measured up to 36 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA4623113 | B | Activation of ESD K213A mutant (unknown origin) expressed in HEK293T cells transfected with p-EGFP assessed as increase in protein mono ubiquitination at 0.1 to 1 uM measured up to 36 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4623114 | B | Activation of human ESD expressed in HEK293T cells transfected with pEGFP-N1 assessed as induction of protein mono ubiquitination at 5 uM after 3 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA4623115 | B | Activation of human ESD expressed in HEK293T cells transfected with pEGFP-N1 assessed as induction of protein mono ubiquitination at 1 to 5 uM after 6 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA4623116 | B | Activation of human ESD expressed in HEK293T cells transfected with pEGFP-N1 assessed as increase in protein mono ubiquitination at 0.1 to 5 uM after 12 to 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA4623117 | B | Activation of ESD K180A mutant (unknown origin) expressed in HEK293T cells transfected with p-EGFP assessed as protein mono ubiquitination at 0.1 to 1 uM measured up to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA4623118 | B | Activation of ESD K213A mutant (unknown origin) expressed in HEK293T cells transfected with p-EGFP assessed as induction of protein mono ubiquitination at 0.1 to 1 uM measured up to 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA4623119 | B | Activation of ESD K180A mutant (unknown origin) expressed in human HeLa cells transfected with p-EGFP assessed as compound co-localization with protein by fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA4623120 | B | Activation of ESD K213A mutant (unknown origin) expressed in human HeLa cells transfected with p-EGFP assessed as protein co-localization by fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4623121 | B | Activation of ESD K180A mutant (unknown origin) expressed in human HeLa cells transfected with p-EGFP at 0.1 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA4623122 | B | Activation of ESD K213A mutant (unknown origin) expressed in human HeLa cells transfected with p-EGFP at 0.1 uM | Homo sapiens | 1 | cell-based format | Scientific Literature |