# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4605389 | B | Inhibition of N-terminal His6-tagged Plasmodium falciparum DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assay | Plasmodium falciparum | 71 | cell-based format | Scientific Literature | ||
2. | ALA4605390 | B | Inhibition of N-terminal His6-tagged Plasmodium vivax DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assay | Plasmodium vivax | 71 | cell-based format | Scientific Literature | ||
3. | ALA4605391 | A | Inhibition of C-terminal His6-tagged human DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assay | Homo sapiens | 72 | cell-based format | Scientific Literature | ||
4. | ALA4605392 | F | Antimalarial activity against Plasmodium falciparum 3D7 infected in human red blood cells after 72 hrs by SYBR Green 1 dye based fluorescence assay | Plasmodium falciparum | 72 | organism-based format | Scientific Literature | ||
5. | ALA4605396 | A | Inhibition of C-terminal His6-tagged mouse DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assay | Mus musculus | 8 | cell-based format | Scientific Literature | ||
6. | ALA4605397 | A | Inhibition of C-terminal His6-tagged rat DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assay | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
7. | ALA4605398 | A | Inhibition of C-terminal His6-tagged dog DHODH expressed in Escherichia coli BL21(DE3) cells using L-DHO as substrate by DCIP dye based assay | Canis lupus familiaris | 8 | cell-based format | Scientific Literature | ||
8. | ALA4605399 | P | Distribution coefficient, log D of compound at pH 7.4 | 26 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA4605400 | P | Kinetic solubility of compound in pH 6.5 phosphate buffered saline | 26 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA4605402 | A | Intrinsic clearance in human liver microsomes assessed as per mg protein | Homo sapiens | 26 | microsome format | Scientific Literature | ||
11. | ALA4605403 | A | Intrinsic clearance in mouse liver microsomes assessed as per mg protein | Mus musculus | 26 | microsome format | Scientific Literature | ||
12. | ALA4605513 | A | Binding affinity to albumin (unknown origin) by chromatographic method | Homo sapiens | 26 | single protein format | Scientific Literature | ||
13. | ALA4812655 | B | Inhibition of Plasmodium falciparum DHODH expressed in Escherichia coli BL21-DE3 using L-dihydroorotate as substrate by steady-state DCIP method | Plasmodium falciparum | 107 | assay format | Scientific Literature | ||
14. | ALA4812656 | B | Inhibition of Plasmodium vivax DHODH expressed in Escherichia coli BL21-DE3 using L-dihydroorotate as substrate by steady-state DCIP method | Plasmodium vivax | 65 | assay format | Scientific Literature | ||
15. | ALA4812657 | A | Inhibition of human DHODH expressed in Escherichia coli BL21-DE3 using L-dihydroorotate as substrate by steady-state DCIP method | Homo sapiens | 67 | assay format | Scientific Literature | ||
16. | ALA4812658 | F | Antimalarial activity against drug-resistant Plasmodium falciparum 3D7 infected in human erythrocytes assessed as reduction in parasite growth measured after 72 hrs by SYBR Green method | Plasmodium falciparum | 107 | organism-based format | Scientific Literature |