#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4621820	F	Inhibition of pyroptosis in LPS-primed immortalized mouse J744A.1 cells followed by subsequent nigericin stimulation by imaging analysis	Mus musculus	3	ALA4619791	cell-based format	Scientific Literature
2.	ALA4621821	F	Inhibition of pyroptosis in LPS-primed immortalized mouse J744A.1 cells assessed as reduction in nigericin-induced IL-beta secretion by imaging analysis	Mus musculus	6	ALA4619791	cell-based format	Scientific Literature
3.	ALA4621822	A	Toxicity in zebrafish embryo	Danio rerio	6	ALA4619791	assay format	Scientific Literature
4.	ALA4621823	P	Lipid-water partition coefficient, logP of the compound		1	ALA4619791	small-molecule physicochemical format	Scientific Literature
5.	ALA4621824	F	Inhibition of pyroptosis in LPS-primed C57BL/6 mouse primary BMDM assessed as effect on nigericin-induced cell morphological changes at 5 uM by propidium iodide staining based confocal microscopy	Mus musculus	1	ALA4619791	cell-based format	Scientific Literature
6.	ALA4621825	F	Inhibition of pyroptosis cell death in LPS-primed immortalized mouse J744A.1 cells assessed as effect on nigericin-induced cell morphological changes by propidium iodide staining based confocal microscopy	Mus musculus	1	ALA4619791	cell-based format	Scientific Literature
7.	ALA4621826	F	Inhibition of pyroptosis cell death in LPS-primed C57BL/6 mouse primary BMDM assessed as reduction in nigericin-induced IL-1beta secretion	Mus musculus	1	ALA4619791	cell-based format	Scientific Literature
8.	ALA4621827	F	Inhibition of pyroptosis in LPS-primed C57BL/6 mouse primary BMDM assessed as reduction in nigericin-induced cell death by Alamar blue assay	Mus musculus	1	ALA4619791	cell-based format	Scientific Literature
9.	ALA4621828	F	Inhibition of pyroptosis in LPS-primed human THP1 assessed as reduction in nigericin-induced cell death at 0.1 to 20 uM by LDH assay	Homo sapiens	1	ALA4619791	cell-based format	Scientific Literature
10.	ALA4621829	F	Inhibition of pyroptosis in LPS-primed human THP1 assessed as reduction in nigericin-induced pyroptotic-pore formation by propidium iodide uptake assay	Homo sapiens	1	ALA4619791	cell-based format	Scientific Literature
11.	ALA4621830	B	Activation of NLRP3 inflammasome in LPS-primed mouse J744A.1 cells assessed as suppression of ATP-induced pyroptosis at 5 uM	Mus musculus	1	ALA4619791	cell-based format	Scientific Literature
12.	ALA4621831	B	Antagonist activity at CCKB receptor in immortalized mouse J744A.1 cells assessed as inhibition of nigericin-induced pyroptosis at 5 uM	Mus musculus	1	ALA4619791	cell-based format	Scientific Literature
13.	ALA4621832	B	Inhibition of GSDMD cytosol-plasma membrane translocation in LPS-primed immortalized mouse J744A.1 cells at 5 uM followed by subsequent nigericin stimulation by immunofluorescence assay	Mus musculus	1	ALA4619791	cell-based format	Scientific Literature
14.	ALA4621833	B	Inhibition of GSDMD cytosol-plasma membrane translocation in LPS-primed C57BL/6 mouse primary BMDM at 5 uM followed by nigericin stimulation by immunofluorescence assay	Mus musculus	1	ALA4619791	assay format	Scientific Literature
15.	ALA4621834	B	Inhibition of N-terminal GSDMD p30 fragment-mediated pyroptotic-cell death in doxycyclin-treated human HEK293T cells assessed as cell death at 5 uM by LDH assay	Homo sapiens	1	ALA4619791	cell-based format	Scientific Literature
16.	ALA4621835	B	Inhibition of caspase-1 activity in LPS-primed immortalized mouse J744A.1 cells assessed as reduction in nigericin-induced GSDMD cleavage at 5 uM by Western blot analysis	Mus musculus	1	ALA4619791	cell-based format	Scientific Literature
17.	ALA4621836	B	Inhibition of caspase-1 activity in LPS-primed immortalized mouse J744A.1 cells assessed as reduction in nigericin-induced Ac-YVAD-pNA cleavage using Ac-YVAD-pNA as substrate at 5 uM by FAM-FLICA reagent based confocal microscopy	Mus musculus	1	ALA4619791	cell-based format	Scientific Literature
18.	ALA4621837	B	Inhibition of caspase-1 activity in LPS-primed immortalized mouse J744A.1 cells assessed as reduction in nigericin-induced caspase-1 cleavage at 5 uM by Western blot analysis	Mus musculus	1	ALA4619791	cell-based format	Scientific Literature
19.	ALA4621838	B	Inhibition of caspase-8 activity in LPS-primed immortalized mouse J744A.1 cells assessed as reduction in nigericin-induced caspase-8 cleavage at 5 uM by Western blot analysis	Mus musculus	1	ALA4619791	cell-based format	Scientific Literature
20.	ALA4621839	F	Inhibition of caspase-1 recruitment to inflammasome in LPS-primed immortalized mouse J744A.1 cells assessed as nigericin-induced colocalization of caspase-1 and ASC at 5 uM by immunostaining based confocal microscopy	Mus musculus	1	ALA4619791	cell-based format	Scientific Literature