| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4618909 | B | Inhibition of wild type human Naa50 (1852 to 2082 residues) expressed in Escherichia coli BL21(DE3) cells using MLGPEGGEGK peptide as substrate after 75 mins in presence of acetyl CoA by rapidfire mass spectrometry analysis | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 2. | ALA4618910 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells in presence of acetyl CoA by SPR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4618911 | B | Binding affinity to Naa50 in human A549 cell lysates assessed as thermal stabilization of protein at 50 uM after 30 mins followed by heating at 40 to 64 degC for 3 mins by immunoblot-based CESTA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4618912 | B | Binding affinity to Naa10 in human A549 cell lysates assessed as thermal stabilization of protein at 50 uM after 30 mins followed by heating at 40 to 64 degC for 3 mins by immunoblot-based CESTA | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4618913 | B | Binding affinity to Naa60 in human A549 cell lysates assessed as thermal stabilization of protein at 50 uM after 30 mins followed by heating at 40 to 64 degC for 3 mins by immunoblot-based CESTA | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4618917 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells assessed as association rate constant in presence of acetyl-CoA by SPR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4618919 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells assessed as dissociation rate constant in presence of acetyl-CoA by SPR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA4618921 | B | Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells assessed as half life for dissociation in presence of acetyl-CoA by SPR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature |
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