# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4629225 | A | Prodrug activation assessed as PSA-mediated (unknown origin) Leu-PAB-DT metabolite formation measured up to 48 hrs by HPLC analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA4629226 | A | Stability assessed as PSA-mediated (unknown origin) compound cleavage by measuring parent compound remaining after 48 hrs by HPLC analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA4629229 | A | Prodrug activation assessed as PSA-mediated (unknown origin) diethyldithiocarbamate formation in presence of leucine aminopeptidase by LC-MS analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
4. | ALA4629230 | A | Prodrug activation assessed as PSA-mediated (unknown origin) Cu(diethyldithiocarbamate)2 complex formation in presence of leucine aminopeptidase and CuSO4 after 14.5 mins by LC-MS analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
5. | ALA4629233 | A | Prodrug activation in human LNCAP cell lysates assessed as PSA-mediated peptide cleavage measured up to 4 hrs by HPLC analysis | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
6. | ALA4629235 | A | Prodrug activation in human PC3 cell lysate assessed as peptide cleavage measured up to 48 hrs by HPLC analysis | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
7. | ALA4629236 | F | Antiproliferative activity against human LNCAP cells assessed as reduction in cell viability after 24 hrs in presence of 1 uM CuSO4 by resazurin dye based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA4629237 | A | Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 24 hrs in presence of CuSO4 by resazurin dye based assay | Homo sapiens | 2 | cell-based format | Scientific Literature |