# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4615734 | B | Inhibition of HDAC6 in mouse N2A cells assessed as increase in alpha tubulin acetylation | Mus musculus | 3 | cell-based format | Scientific Literature | ||
2. | ALA4615735 | B | Inhibition of HDAC1 in mouse N2A cells | Mus musculus | 3 | cell-based format | Scientific Literature | ||
3. | ALA4615736 | B | Inhibition of HDAC6 in mouse N2A cells | Mus musculus | 3 | cell-based format | Scientific Literature | ||
4. | ALA4615737 | B | Selectivity index, ratio of IC50 for HDAC1 in mouse N2A cells to IC50 for HDAC6 in mouse N2A cells | Mus musculus | 3 | cell-based format | Scientific Literature | ||
5. | ALA4615738 | B | Ratio of EC50 for inhibition of HDAC6 in mouse N2A cells assessed as alpha tubulin acetylation to IC50 for HDAC6 in mouse N2A cells | Mus musculus | 3 | cell-based format | Scientific Literature | ||
6. | ALA4615739 | A | Efflux ratio of permeability in MDCK-MDR1 cells | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
7. | ALA4615740 | A | Drug concentration in CD-1 mouse brain at 3 mg/kg, iv measured at 8 mins | Mus musculus | 3 | organism-based format | Scientific Literature | ||
8. | ALA4615741 | A | Drug concentration in CD-1 mouse brain at 3 mg/kg, iv measured at 60 mins | Mus musculus | 3 | organism-based format | Scientific Literature | ||
9. | ALA4615742 | A | Drug concentration in CD-1 mouse plasma at 3 mg/kg, iv measured at 8 mins | Mus musculus | 3 | organism-based format | Scientific Literature | ||
10. | ALA4615743 | A | Drug concentration in CD-1 mouse plasma at 3 mg/kg, iv measured at 60 mins | Mus musculus | 3 | organism-based format | Scientific Literature | ||
11. | ALA4615744 | A | Ratio of drug level in brain to plasma in CD-1 mouse at 3 mg/kg, iv measured after 8 mins | Mus musculus | 3 | organism-based format | Scientific Literature | ||
12. | ALA4615745 | A | Ratio of drug level in brain to plasma in CD-1 mouse at 3 mg/kg, iv measured after 60 mins | Mus musculus | 3 | organism-based format | Scientific Literature | ||
13. | ALA4615748 | F | In vivo inhibition of HDAC6 in C57BL/6 mouse cortex assessed as increase in alpha tubulin acetylation at 20 mg/kg, ip administered bid with interval of 4 hrs and measured after 1.5 hrs of last dosage by Western blot analysis | Mus musculus | 3 | organism-based format | Scientific Literature |