# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4627646 | Functional | Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1-d2 addition by HTRF assay | Homo sapiens | 25 | ALA4627259 | cell-based format | Scientific Literature | |
2. | ALA4627647 | Functional | Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate at 30 uM to 1 nM incubated for 1 hr followed by IP1-d2 addition by HTRF assay relative to control | Homo sapiens | 25 | ALA4627259 | cell-based format | Scientific Literature | |
3. | ALA4627648 | ADME | Drug metabolism in mouse microsomes assessed as drug turnover at 20 uM measured after 30 mins by LCMS analysis | Mus musculus | 25 | ALA4627259 | microsome format | Scientific Literature | |
4. | ALA4627649 | ADME | Drug metabolism in rat microsomes assessed as drug turnover at 20 uM measured after 30 mins by LCMS analysis | Rattus norvegicus | 25 | ALA4627259 | microsome format | Scientific Literature | |
5. | ALA4627650 | ADME | Drug metabolism in dog microsomes assessed as drug turnover at 20 uM measured after 30 mins by LCMS analysis | Canis lupus familiaris | 25 | ALA4627259 | microsome format | Scientific Literature | |
6. | ALA4627651 | ADME | Drug metabolism in human microsomes assessed as drug turnover at 20 uM measured after 30 mins by LCMS analysis | Homo sapiens | 25 | ALA4627259 | microsome format | Scientific Literature | |
7. | ALA4742494 | Functional | Agonist activity at human GPR142 expressed in HEK293 cells assessed as IP1 accumulation incubated for 1 hr by IP-one HTRF assay | Homo sapiens | 3 | ALA4742391 | cell-based format | Patent Bioactivity Data | |
8. | ALA4742495 | Functional | Agonist activity at human GPR142 expressed in HEK293 cells assessed as IP1 accumulation incubated for 1 hr by IP-one HTRF assay relative to control | Homo sapiens | 3 | ALA4742391 | cell-based format | Patent Bioactivity Data |