# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4622293 | B | Inhibition of MRS4174 binding to human P2Y14R expressed in CHO cells pre-incubated for 30 mins before MRS4174 addition and further incubated for 30 mins at pH 7.4 by flow cytomtery based competitive fluorescence assay | Homo sapiens | 29 | ALA4619807 | cell-based format | Scientific Literature | |
2. | ALA4622294 | B | Inhibition of MRS4174 binding to mouse P2Y14R expressed in HEK293 cells pre-incubated for 30 mins before MRS4174 addition and further incubated for 30 mins by flow cytomtery based competitive fluorescence assay | Mus musculus | 13 | ALA4619807 | cell-based format | Scientific Literature | |
3. | ALA4622295 | B | Selectivity index, ratio of IC50 for inhibition of MRS4174 binding to human P2Y14R expressed in CHO cells to IC50 for inhibition of MRS4174 binding to mouse P2Y14R expressed in HEK292 cells | Homo sapiens | 8 | ALA4619807 | cell-based format | Scientific Literature | |
4. | ALA4622299 | B | Binding affinity to DOR (unknown origin) | Homo sapiens | 6 | ALA4619807 | single protein format | Scientific Literature | |
5. | ALA4622300 | B | Binding affinity to sigma 2 receptor (unknown origin) | Homo sapiens | 7 | ALA4619807 | assay format | Scientific Literature |