# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4604222 | B | Protac activity at CRBN/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 1 uM after 12 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
2. | ALA4604223 | B | Protac activity at CRBN/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 30 uM after 12 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
3. | ALA4604224 | B | Protac activity at CRBN/CDK2 in AR-negative human PC3 cells assessed as induction of CDK2 protein degradation at 50 nM after 12 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA4604225 | B | Protac activity at CRBN/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 50 nM after 12 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA4604226 | F | Antiproliferative activity against AR-negative human PC3 cells assessed as reduction in cell viability after 5 days by CCK8 assay | Homo sapiens | 22 | cell-based format | Scientific Literature |