# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4612962 | Binding | Inhibition of recombinant human N-terminal His6-tagged DCLK1 (G351 to H689 residues) expressed in Escherichia coli BL21 DE3 using 5-FAM-KKLRRTLSVA-COOH as substrate measured after 2 hrs by mobility shift assay | Homo sapiens | 38 | ALA4610122 | assay format | Scientific Literature | |
2. | ALA4612963 | Binding | Inhibition of ERK5 (unknown origin) at 10 uM by cell-based KiNativ profiling method | Homo sapiens | 24 | ALA4610122 | cell-based format | Scientific Literature | |
3. | ALA4612964 | Binding | Inhibition of ERK5 in human HeLa cells assessed as reduction in EGF-induced ERK5 autophosphorylation pretreated for 1 hr followed by EGF stimulation and measured after 17 mins by 32p kinase assay | Homo sapiens | 16 | ALA4610122 | cell-based format | Scientific Literature | |
4. | ALA4612965 | Binding | Inhibition of recombinant human GST-tagged LRRK2 catalytic domain (970 to 2527 residues) expressed in baculovirus expression system using LRRKtide as substrate measured after 1 hr by Alexa fluor-647 ADP tracer-based ADAPTA assay | Homo sapiens | 36 | ALA4610122 | assay format | Scientific Literature |