# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4605789 | B | Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-luciferase reporter gene assay | Homo sapiens | 11 | ALA4602715 | cell-based format | Scientific Literature | |
2. | ALA4605825 | B | Inhibition of TEL/KDR (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-luciferase reporter gene assay | Homo sapiens | 9 | ALA4602715 | cell-based format | Scientific Literature | |
3. | ALA4605826 | A | Cytotoxicity against human LC2/ad cells assessed as reduction in cell viability incubated for 6 days by CellTiter Glo assay | Homo sapiens | 9 | ALA4602715 | cell-based format | Scientific Literature | |
4. | ALA4605827 | B | Inhibition of CCDC6/RET (unknown origin) transfected in human LC2/ad cells assessed as reduction in cell viability incubated for 6 days by CellTiter Glo assay | Homo sapiens | 7 | ALA4602715 | cell-based format | Scientific Literature | |
5. | ALA4605831 | A | Clearance in BALB/c mouse at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | ALA4602715 | organism-based format | Scientific Literature | |
6. | ALA4605832 | A | Volume of distribution at steady state in BALB/c mouse at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | ALA4602715 | organism-based format | Scientific Literature | |
7. | ALA4605833 | A | Half life in BALB/c mouse at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | ALA4602715 | organism-based format | Scientific Literature | |
8. | ALA4605834 | A | AUC in BALB/c mouse at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | ALA4602715 | organism-based format | Scientific Literature | |
9. | ALA4605835 | A | Cmax in BALB/c mouse at 2 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | ALA4602715 | organism-based format | Scientific Literature | |
10. | ALA4605836 | A | Half life in BALB/c mouse at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | ALA4602715 | organism-based format | Scientific Literature | |
11. | ALA4605837 | A | AUC in BALB/c mouse at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | ALA4602715 | organism-based format | Scientific Literature | |
12. | ALA4605838 | A | Cmax in BALB/c mouse at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | ALA4602715 | organism-based format | Scientific Literature | |
13. | ALA4605839 | A | Oral bioavailability in BALB/c mouse at 10 mg/kg measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | ALA4602715 | organism-based format | Scientific Literature | |
14. | ALA4605858 | B | Displacement of [3H]-dofetilide from human ERG expressed in CHO cells incubated for 90 mins by microbeta scintillation counting method | Homo sapiens | 4 | ALA4602715 | cell-based format | Scientific Literature | |
15. | ALA4605859 | B | Inhibition of human ERG expressed in human embryonic kidney cells by manual patch clamp assay | Homo sapiens | 4 | ALA4602715 | cell-based format | Scientific Literature |