# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4605875 | Binding | Protac activity at VHL/HDAC6 in human MM1S cells assessed as HDAC6 degradation at 100 nM measured after 6 hrs by ELISA | Homo sapiens | 11 | ALA4602716 | cell-based format | Scientific Literature | |
2. | ALA4605876 | Binding | Protac activity at VHL/HDAC6 in human MM1S cells assessed as HDAC6 degradation at 100 nM measured after 6 hrs by Western blot analysis | Homo sapiens | 5 | ALA4602716 | cell-based format | Scientific Literature | |
3. | ALA4605877 | Binding | Protac activity at VHL/HDAC6 in human MM1S cells assessed as increase in tubulin acetylation at 100 nM measured after 6 hrs by Western blot analysis | Homo sapiens | 3 | ALA4602716 | cell-based format | Scientific Literature | |
4. | ALA4605879 | Binding | Protac activity at VHL/HDAC6 in human MM1S cells measured after 6 hrs by ELISA | Homo sapiens | 2 | ALA4602716 | cell-based format | Scientific Literature | |
5. | ALA4605881 | Binding | Protac activity at VHL/HDAC6 in human MM1S cells measured after 6 hrs by ELISA relative to control | Homo sapiens | 2 | ALA4602716 | cell-based format | Scientific Literature | |
6. | ALA4605882 | Binding | Protac activity at VHL/HDAC6 in human MM1S cells assessed as HDAC6 degradation at 10 nM measured after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
7. | ALA4605883 | Binding | Protac activity at VHL/HDAC6 in human MM1S cells assessed as HDAC6 degradation at 100 nM measured after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
8. | ALA4605884 | Binding | Protac activity at VHL/HDAC6 in human MM1S cells assessed as compound-VHL complex formation at 3 uM after 6 hrs | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
9. | ALA4605885 | Binding | Protac activity at VHL/HDAC6 in human MM1S cells assessed as compound-HDAC6 complex formation at 3 uM after 6 hrs | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
10. | ALA4605886 | Binding | Protac activity at VHL/HDAC6 in human MM1S cells assessed as induction of tubulin acetylation after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
11. | ALA4605887 | Binding | Protac activity at VHL/HDAC6 in human MM1S cells assessed as induction of tubulin acetylation at 1 uM after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
12. | ALA4605888 | Binding | Protac activity at VHL/HDAC6 in human MM1S cells assessed as increase in tubulin acetylation at 300 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
13. | ALA4605889 | Binding | Protac activity at VHL/HDAC1 in human MM1S cells assessed as HDAC1 degradation at 100 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
14. | ALA4605890 | Binding | Protac activity at VHL/HDAC2 in human MM1S cells assessed as HDAC2 degradation at 100 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
15. | ALA4605891 | Binding | Protac activity at VHL/HDAC3 in human MM1S cells assessed as HDAC3 degradation at 100 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
16. | ALA4605892 | Binding | Protac activity at VHL/HDAC4 in human MM1S cells assessed as HDAC4 degradation at 100 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
17. | ALA4605893 | Binding | Protac activity at VHL/HDAC5 in human MM1S cells assessed as HDAC5 degradation at 100 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
18. | ALA4605894 | Binding | Protac activity at VHL/HDAC7 in human MM1S cells assessed as HDAC7 degradation at 100 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
19. | ALA4605895 | Binding | Protac activity at VHL/IKZF1 in human MM1S cells assessed as IKZF1 degradation at 100 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature | |
20. | ALA4605896 | Binding | Protac activity at VHL/IKZF3 in human MM1S cells assessed as IKZF3 degradation at 100 nM after 4 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602716 | cell-based format | Scientific Literature |