# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4603149 | F | Antiproliferative activity against human MGC803 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 13 | ALA4602611 | cell-based format | Scientific Literature | |
2. | ALA4603150 | F | Antiproliferative activity against human PC3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 13 | ALA4602611 | cell-based format | Scientific Literature | |
3. | ALA4603151 | F | Antiproliferative activity against human EC109 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 13 | ALA4602611 | cell-based format | Scientific Literature | |
4. | ALA4603152 | B | Inhibition of NAE-mediated neddylation in human MGC803 cells assessed as reduction in Nedd8-Cullin1 adduct formation by Western blot analysis | Homo sapiens | 2 | ALA4602611 | cell-based format | Scientific Literature | |
5. | ALA4603153 | B | Inhibition of NAE (unknown origin)-mediated neddylation assessed as decrease in Nedd8-Ubcl2 adduct formation at 5 uM by Western blot analysis | Homo sapiens | 1 | ALA4602611 | single protein format | Scientific Literature | |
6. | ALA4603155 | B | Inhibition of NAE-mediated neddylation in human MGC803 cells assessed as reduction in Nedd8-Ubcl2 adduct formation incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
7. | ALA4603156 | B | Inhibition of NAE-mediated neddylation in human MGC803 cells assessed as reduction in Nedd8-Ubcl2 adduct formation at 5 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
8. | ALA4603157 | B | Inhibition of NAE-mediated neddylation in human MGC803 cells assessed as reduction in Nedd8-Ubcl2 adduct formation at 10 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
9. | ALA4603158 | B | Inhibition of NAE-mediated neddylation in human MGC803 cells assessed as reduction in Nedd8-Cullin3 adduct formation at 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
10. | ALA4603159 | B | Inhibition of NAE-mediated neddylation in human MGC803 cells assessed as reduction in NAE1-Nedd8 adduct formation at 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
11. | ALA4603160 | F | Increase in p21 protein expression in human MGC803 cells at 5 to 20 umol/l incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
12. | ALA4603161 | F | Increase in ATF4 protein expression in human MGC803 cells at 5 to 20 umol/l incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
13. | ALA4603162 | F | Increase in CHOP protein expression in human MGC803 cells at 5 to 20 umol/l incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
14. | ALA4603163 | F | Increase in DR5 protein expression in human MGC803 cells at 5 to 20 umol/l incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
15. | ALA4603164 | F | Increase in Noxa protein expression in human MGC803 cells at 5 to 20 umol/l incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
16. | ALA4603165 | F | Inhibition of colony formation in human MGC803 cells at 0.5 uM incubated for 7 days by crystal violet staining based assay | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
17. | ALA4603166 | F | Inhibition of colony formation in human MGC803 cells by crystal violet staining based assay | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
18. | ALA4603167 | F | Induction of cell cycle arrest in human MGC803 cells assessed as accumulation in G2/M phase at 5 to 20 umol/l incubated for 24 hrs by propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
19. | ALA4603168 | F | Induction of cell cycle arrest in human MGC803 cells assessed as fold change in accumulation in G2/M phase at 5 to 20 umol/l incubated for 24 hrs by propidium iodide staining based flow cytometric analysis relative to control | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature | |
20. | ALA4603169 | F | Downregulation of Cyclin B1 protein expression in human MGC803 cells at 5 to 20 umol/l incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4602611 | cell-based format | Scientific Literature |