# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4627020 | B | Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled ribonucleotide monophosphates incorporation into RNA using cIRES template measured after 2 hrs by microscintillation counting method | Hepatitis C virus | 10 | single protein format | Scientific Literature | ||
2. | ALA4627021 | B | Inhibition of HCV NS5B RNA-dependent RNA polymerase 10-mer elongation complex assessed as chain termination of RNA synthesis by measuring reduction in 11-mer RNA product formation at 100 uM incubated for 1 min by polyacrylamide gel based method | Hepatitis C virus | 1 | single protein format | Scientific Literature | ||
3. | ALA4627022 | B | Inhibition of HCV NS5B RNA-dependent RNA polymerase 10-mer elongation complex assessed as chain termination of RNA synthesis by measuring reduction in 20-mer RNA product formation at 100 uM incubated for 1 min in presence of UTP and ATP by polyacrylamide gel based method | Hepatitis C virus | 1 | single protein format | Scientific Literature | ||
4. | ALA4627023 | A | Inhibition of human DNA polymerase alpha at 100 uM using calf DNA as substrate by microbeta scintillation counting method relative to control | Homo sapiens | 6 | single protein format | Scientific Literature | ||
5. | ALA4627024 | A | Inhibition of human DNA polymerase beta at 100 uM using calf DNA as substrate by microbeta scintillation counting method relative to control | Homo sapiens | 6 | single protein format | Scientific Literature | ||
6. | ALA4627025 | A | Inhibition of human DNA polymerase gamma at 100 uM using calf DNA as substrate by microbeta scintillation counting method relative to control | Homo sapiens | 6 | assay format | Scientific Literature | ||
7. | ALA4627026 | A | Inhibition of RNA polymerase 2 in human HeLa cell nuclear extract assessed as reduction in RNA transcription by polyacrylamide gel electrophoresis method | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
8. | ALA4627027 | B | Substrate activity at human mitochondrial RNA polymerase assessed as nucleotide incorporation into RNA at 100 uM using [33P]-labeled 5'-UUUUGCCGCGCC-3' and 3'-CGGCGCGGCACGTAAGGG-5' RNA/DNA primer/template by polyacrylamide gel electrophoresis method | Homo sapiens | 6 | assay format | Scientific Literature |