# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4623432 | Functional | Cytotoxicity against human SK-MEL-147 cells assessed as reduction in cell viability at 50 and 100 uM after 24 hrs by MTT assay | Homo sapiens | 23 | ALA4622851 | cell-based format | Scientific Literature | |
2. | ALA4623433 | Functional | Cytotoxicity against human Jurkat cells assessed as reduction in cell viability at 50 and 100 uM after 24 hrs by MTT assay | Homo sapiens | 23 | ALA4622851 | cell-based format | Scientific Literature | |
3. | ALA4623434 | Functional | Cytotoxicity against human SK-MEL-147 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 23 | ALA4622851 | cell-based format | Scientific Literature | |
4. | ALA4623435 | Functional | Cytotoxicity against human Jurkat cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 23 | ALA4622851 | cell-based format | Scientific Literature | |
5. | ALA4623461 | Binding | Inhibition of Leishmania mexicana rCPB2.8 using Z-FR-AMC as substrate by spectrofluorometric analysis | Leishmania mexicana | 5 | ALA4622851 | single protein format | Scientific Literature | |
6. | ALA4623462 | Binding | Inhibition of Leishmania mexicana rCPB3.0 using Z-FR-AMC as substrate by spectrofluorometric analysis | Leishmania mexicana | 5 | ALA4622851 | assay format | Scientific Literature | |
7. | ALA4623463 | Binding | Inhibition of Leishmania mexicana rCPB3.0 H84Y mutant using Z-FR-AMC as substrate by spectrofluorometric analysis | Leishmania mexicana | 5 | ALA4622851 | assay format | Scientific Literature | |
8. | ALA4623464 | Binding | Inhibition of Leishmania mexicana rCPB2.8 assessed as inhibition constant using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by Lineweaver-Burk double reciprocal plot analysis | Leishmania mexicana | 1 | ALA4622851 | single protein format | Scientific Literature | |
9. | ALA4623465 | Binding | Inhibition of Leishmania mexicana rCPB3.0 assessed as inhibition constant using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by Lineweaver-Burk double reciprocal plot analysis | Leishmania mexicana | 1 | ALA4622851 | assay format | Scientific Literature | |
10. | ALA4623466 | Binding | Inhibition of Leishmania mexicana rCPB3.0 H84Y mutant assessed as inhibition constant using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by Lineweaver-Burk double reciprocal plot analysis | Leishmania mexicana | 1 | ALA4622851 | assay format | Scientific Literature | |
11. | ALA4623467 | Binding | Inhibition of Leishmania mexicana rCPB2.8 assessed as inhibition constant for uncompetitive inhibition using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by Lineweaver-Burk double reciprocal plot analysis | Leishmania mexicana | 1 | ALA4622851 | single protein format | Scientific Literature | |
12. | ALA4623468 | Binding | Inhibition of Leishmania mexicana rCPB3.0 assessed as inhibition constant for uncompetitive inhibition using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by Lineweaver-Burk double reciprocal plot analysis | Leishmania mexicana | 1 | ALA4622851 | assay format | Scientific Literature | |
13. | ALA4623469 | Binding | Inhibition of Leishmania mexicana rCPB3.0 H84Y mutant assessed as inhibition constant for uncompetitive inhibition using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition by Lineweaver-Burk double reciprocal plot analysis | Leishmania mexicana | 1 | ALA4622851 | assay format | Scientific Literature |