# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4622293 | B | Inhibition of MRS4174 binding to human P2Y14R expressed in CHO cells pre-incubated for 30 mins before MRS4174 addition and further incubated for 30 mins at pH 7.4 by flow cytomtery based competitive fluorescence assay | Homo sapiens | 29 | ALA4619807 | cell-based format | Scientific Literature | |
2. | ALA4622294 | B | Inhibition of MRS4174 binding to mouse P2Y14R expressed in HEK293 cells pre-incubated for 30 mins before MRS4174 addition and further incubated for 30 mins by flow cytomtery based competitive fluorescence assay | Mus musculus | 13 | ALA4619807 | cell-based format | Scientific Literature | |
3. | ALA4622300 | B | Binding affinity to sigma 2 receptor (unknown origin) | Homo sapiens | 7 | ALA4619807 | assay format | Scientific Literature | |
4. | ALA4622312 | P | Aqueous solubility at pH 7.4 by pION method | 6 | ALA4619807 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4622313 | P | Aqueous solubility at pH 4 by pION method | 6 | ALA4619807 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4622314 | P | Lipophilicity, change in Constant K of the compound by RP-HPLC analysis relative to PPTN | 6 | ALA4619807 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4622324 | A | Unbound fraction in human plasma | Homo sapiens | 4 | ALA4619807 | cell-free format | Scientific Literature | |
8. | ALA4622325 | A | Unbound fraction in mouse plasma | Mus musculus | 4 | ALA4619807 | cell-free format | Scientific Literature | |
9. | ALA4622326 | A | Unbound fraction in rat plasma | Rattus norvegicus | 4 | ALA4619807 | cell-free format | Scientific Literature |