| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4624479 | B | Inhibition of GlyT1 in rat primary cortical neurons assessed as reduction in radiolabeled glycine uptake by scintillation proximity assay | Rattus norvegicus | 10 | assay format | Scientific Literature | ||
| 2. | ALA4624480 | B | Inhibition of human GlyT1 expressed in human HEK cells assessed as reduction in radiolabeled glycine uptake by scintillation proximity assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 3. | ALA4624481 | A | Metabolic stability in rat liver microsomes assessed as intrisic clearance | Rattus norvegicus | 10 | microsome format | Scientific Literature | ||
| 4. | ALA4624482 | A | Metabolic stability in human liver microsomes assessed as intrisic clearance | Homo sapiens | 10 | microsome format | Scientific Literature | ||
| 5. | ALA4624483 | B | Inhibition of human ERG expressed in CHO cells by electrophysiology QPatch assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 6. | ALA4624484 | A | Efflux ratio of permeability from MDCK-MDR1 cells | Canis lupus familiaris | 10 | cell-based format | Scientific Literature | ||
| 7. | ALA4624485 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4624486 | A | Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4624487 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4624488 | A | Tmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4624489 | A | Cmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4624490 | A | AUC (0 to infinity) in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4624491 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4624492 | P | Kinetic solubility of compound | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 15. | ALA4624493 | A | Permeability of compound by PAMPA | 1 | assay format | Scientific Literature | |||
| 16. | ALA4624494 | A | Permeability of compound in MDCK cells | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4624495 | A | Drug concentration in Sprague-Dawley rat brain at 10 mg/kg, po measured after 90 mins | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4624496 | A | Drug concentration in Sprague-Dawley rat CSF at 10 mg/kg, po measured after 90 mins | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4624497 | A | Ratio of drug level in brain to plasma of Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4624498 | B | Inhibition of 5-HT2B (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature |
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