# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4629858 | Binding | Binding affinity to CAMK1D (unknown origin) assessed as change in melting temperature at 10 uM by SYPRO Orange dye based fluorescence assay | Homo sapiens | 19 | ALA4627396 | single protein format | Scientific Literature | |
2. | ALA4629865 | Binding | Binding affinity to wild-type human partial length CAMK1D (M1 to K299 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 4 | ALA4627396 | assay format | Scientific Literature | |
3. | ALA4629869 | Binding | Binding affinity to wild-type human partial length MEK5 (L98 to P448 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 4 | ALA4627396 | assay format | Scientific Literature | |
4. | ALA4629870 | Binding | Binding affinity to wild-type human partial length PIP5K1C (M1 to T668 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 3 | ALA4627396 | assay format | Scientific Literature | |
5. | ALA4629872 | Binding | Binding affinity to wild-type human partial length MLK3 (I77 to W399 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 4 | ALA4627396 | assay format | Scientific Literature | |
6. | ALA4629876 | Binding | Inhibition of human CAMK1D using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot kinase assay | Homo sapiens | 6 | ALA4627396 | single protein format | Scientific Literature | |
7. | ALA4629880 | Binding | Inhibition of human MEK5 using ERK5 as substrate in presence of [gamma-33P]-ATP by hotspot kinase assay | Homo sapiens | 4 | ALA4627396 | single protein format | Scientific Literature | |
8. | ALA4629881 | Binding | Inhibition of human PIP5K1C using PI(4)P:PS as substrate by hotspot kinase assay | Homo sapiens | 2 | ALA4627396 | single protein format | Scientific Literature | |
9. | ALA4629883 | Binding | Inhibition of human MLK3 using myelin basic protein as substrate in presence of [gamma-33P]-ATP by hotspot kinase assay | Homo sapiens | 4 | ALA4627396 | single protein format | Scientific Literature | |
10. | ALA4629886 | Binding | Inhibition of recombinant human full-length His-tagged CAMK1D expressed in baculovirus expression system using autocamtide-2 as substrate preincubated for 15 mins followed by ATP addition and measured after 2 hrs by ADP-glo luminescence assay | Homo sapiens | 15 | ALA4627396 | assay format | Scientific Literature | |
11. | ALA4629887 | Binding | Binding affinity to DAPK1 (unknown origin) assessed as change in melting temperature at 10 uM by SYPRO Orange dye based fluorescence assay | Homo sapiens | 12 | ALA4627396 | single protein format | Scientific Literature | |
12. | ALA4629888 | Binding | Binding affinity to CK2a (unknown origin) assessed as change in melting temperature at 10 uM by SYPRO Orange dye based fluorescence assay | Homo sapiens | 12 | ALA4627396 | single protein format | Scientific Literature | |
13. | ALA4629889 | Binding | Binding affinity to ABL (unknown origin) assessed as change in melting temperature at 10 uM by SYPRO Orange dye based fluorescence assay | Homo sapiens | 11 | ALA4627396 | single protein format | Scientific Literature | |
14. | ALA4629890 | Binding | Binding affinity to PIM1 (unknown origin) assessed as change in melting temperature at 10 uM by SYPRO Orange dye based fluorescence assay | Homo sapiens | 12 | ALA4627396 | single protein format | Scientific Literature | |
15. | ALA4629891 | Binding | Binding affinity to wild-type human partial length CAMK1B (W9 to A311 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 3 | ALA4627396 | assay format | Scientific Literature | |
16. | ALA4629892 | Binding | Binding affinity to wild-type human full length CAMK1A (M1 to L370 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 3 | ALA4627396 | assay format | Scientific Literature | |
17. | ALA4629894 | Binding | Inhibition of HA-tagged CAMK1D (unknown origin) expressed in human MDA-MB-231 cells assessed as reduction in CAMK1D autophosphorylation measured after 4 hrs by Western blot analysis | Homo sapiens | 5 | ALA4627396 | cell-based format | Scientific Literature | |
18. | ALA4629895 | Binding | Inhibition of human CAMK1B using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot kinase assay | Homo sapiens | 2 | ALA4627396 | single protein format | Scientific Literature | |
19. | ALA4629896 | Binding | Inhibition of human CAMK1A using KKALRRQETVDAL as substrate in presence of [gamma-33P]-ATP by hotspot kinase assay | Homo sapiens | 2 | ALA4627396 | single protein format | Scientific Literature | |
20. | ALA4629897 | Physicochemical | Lipophilicity, log D of the compound | 2 | ALA4627396 | small-molecule physicochemical format | Scientific Literature |