# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4627123 | F | Potentiation of chloramphenicol-induced antibacterial activity against Enterobacter aerogenes Ea289 assessed as ratio of the chloramphenicol alone MIC to chloramphenicol MIC in presence of MIC/4 level of compound incubated for 18 hrs | Klebsiella aerogenes | 27 | organism-based format | Scientific Literature | ||
2. | ALA4627124 | T | Toxicity in CHO cells assessed as reduction in cell viability incubated for 24 hrs by WST1 assay | Cricetulus griseus | 26 | cell-based format | Scientific Literature | ||
3. | ALA4627125 | F | Potentiation of nalidixic acid-induced antibacterial activity against Enterobacter aerogenes Ea289 assessed as ratio of the nalidixic acid alone MIC to chloramphenicol MIC in presence of MIC/4 level of compound incubated for 18 hrs | Klebsiella aerogenes | 27 | organism-based format | Scientific Literature | ||
4. | ALA4627126 | F | Potentiation of doxycycline-induced antibacterial activity against Enterobacter aerogenes Ea289 assessed as ratio of the doxycycline alone MIC to chloramphenicol MIC in presence of MIC/4 level of compound incubated for 18 hrs | Klebsiella aerogenes | 27 | organism-based format | Scientific Literature | ||
5. | ALA4627127 | F | Potentiation of erythromycin-induced antibacterial activity against Enterobacter aerogenes Ea289 assessed as ratio of the erythromycin alone MIC to chloramphenicol MIC in presence of MIC/4 level of compound incubated for 18 hrs | Klebsiella aerogenes | 27 | organism-based format | Scientific Literature | ||
6. | ALA4627128 | F | Potentiation of chloramphenicol-induced antibacterial activity against Salmonella enterica subsp. enterica serovar Typhimurium BN10055 assessed as ratio of the chloramphenicol alone MIC to chloramphenicol MIC in presence of MIC/4 level of compound incubated for 18 hrs | Salmonella enterica subsp. enterica serovar Typhimurium | 27 | organism-based format | Scientific Literature | ||
7. | ALA4627129 | F | Potentiation of nalidixic acid-induced antibacterial activity against Salmonella enterica subsp. enterica serovar Typhimurium BN10055 assessed as ratio of the nalidixic acid alone MIC to chloramphenicol MIC in presence of MIC/4 level of compound incubated for 18 hrs | Salmonella enterica subsp. enterica serovar Typhimurium | 27 | organism-based format | Scientific Literature | ||
8. | ALA4627130 | F | Potentiation of doxycycline-induced antibacterial activity against Salmonella enterica subsp. enterica serovar Typhimurium BN10055 assessed as ratio of the doxycycline alone MIC to chloramphenicol MIC in presence of MIC/4 level of compound incubated for 18 hrs | Salmonella enterica subsp. enterica serovar Typhimurium | 27 | organism-based format | Scientific Literature | ||
9. | ALA4627131 | F | Potentiation of erythromycin-induced antibacterial activity against Salmonella enterica subsp. enterica serovar Typhimurium BN10055 assessed as ratio of the erythromycin alone MIC to chloramphenicol MIC in presence of MIC/4 level of compound incubated for 18 hrs | Salmonella enterica subsp. enterica serovar Typhimurium | 26 | organism-based format | Scientific Literature | ||
10. | ALA4627132 | F | Potentiation of chloramphenicol-induced antibacterial activity against Enterobacter aerogenes Ea289 assessed as efficiency index by measuring sum of gain factor for each test compound reported for chloramphenicol/nalidixic acid/doxycycline/erythromycin and divided by concentration of test compound | Klebsiella aerogenes | 12 | organism-based format | Scientific Literature | ||
11. | ALA4627133 | F | Potentiation of chloramphenicol-induced antibacterial activity against Salmonella enterica subsp. enterica serovar Typhimurium BN10055 assessed as efficiency index by measuring sum of gain factor for each test compound reported for chloramphenicol/nalidixic acid/doxycycline/erythromycin and divided by concentration of test compound | Salmonella enterica subsp. enterica serovar Typhimurium | 12 | organism-based format | Scientific Literature | ||
12. | ALA4627134 | T | Toxicity index, ratio of IC50 for toxicity in CHO cells to concentration of test compound causing at least 8 times decrease of MIC of almost 3 antibiotics (chloramphenicol/nalidixic acid/doxycycline/erythromycin ) against Enterobacter aerogenes Ea289 | 12 | cell-based format | Scientific Literature | |||
13. | ALA4627135 | T | Toxicity index, ratio of IC50 for toxicity in CHO cells to concentration of test compound causing at least 8 times decrease of MIC of almost 3 antibiotics (chloramphenicol/nalidixic acid/doxycycline/erythromycin ) against Salmonella enterica subsp. enterica serovar Typhimurium BN10055 | 12 | cell-based format | Scientific Literature |